The outbreak of the novel coronavirus disease 2019 (COVID-19) has emerged as one of the
biggest global health threats worldwide. As of October 2020, more than 44 million confirmed …

Abstract Coronavirus disease 2019 (COVID-19) is first detected in December 2019 in
Wuhan, China which is a new pandemic caused by SARS-COV-2 that has greatly affected …

ABSTRACT Background Coronavirus disease 2019 (COVID-19), an acute, sometimes
severe respiratory illness caused by a novel coronavirus has led to a vast pandemic with an …

Patients with severe COVID-19 have a hyperinflammatory immune response suggestive of
macrophage activation. Bruton tyrosine kinase (BTK) regulates macrophage signaling and …

Bruton's tyrosine kinase (BTK) inhibitors, drugs utilized in cancer, are being repurposed for
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)(COVID-19). Recently, BTK …

Bruton's tyrosine kinase (BTK) was discovered due to its importance in B cell development,
and it has a critical role in signal transduction downstream of the B cell receptor (BCR) …

Bruton's tyrosine kinase (BTK) is a TEC kinase with a multifaceted role in B‐cell biology and
function, highlighted by its position as a critical component of the B‐cell receptor signalling …

Abstract Introduction The Bruton tyrosine kinase (BTK) regulates B cell and macrophage
signaling, development, survival, and activation. Inhibiting BTK has been hypothesized to …

Bruton's tyrosine kinase (BTK) signaling is involved in innate immune responses and
regulates the production of proinflammatory cytokines that can contribute to COVID-19 …

Patent Publication Number. WO 2021/018018 A1 Publication Date. February 04, 2021
Priority Application. CN PCT/CN2019/098015 Priority Date. July 26, 2019 Inventors. Huo, C.; …