The pentraxin family in autoimmune disease
Y Li, S Zhang, J Liu, Y Zhang, N Zhang, Q Cheng… - Clinica Chimica …, 2023 - Elsevier
The pentraxins represent a family of multifunctional proteins composed of long and short
pentamers. The latter includes serum amyloid P component (SAP) and C-reactive protein …
pentamers. The latter includes serum amyloid P component (SAP) and C-reactive protein …
Pentraxin 3: A promising therapeutic target for autoimmune diseases
Q Wu, F Cao, J Tao, X Li, SG Zheng, HF Pan - Autoimmunity Reviews, 2020 - Elsevier
Abstract Pentraxin 3 (PTX3) is a prototypic humoral soluble pattern recognition molecule that
exerts a pivotal role in innate immune response and inflammation, as well as in tissue …
exerts a pivotal role in innate immune response and inflammation, as well as in tissue …
Long pentraxin 3 (PTX3) in the light of its structure, mechanism of action and clinical implications
P CieŚlik, A Hrycek - Autoimmunity, 2012 - Taylor & Francis
Pentraxins are a group of evolutionarily conserved ancient proteins. Depending on their
structure, pentraxins are divided into short and long pentraxin families. Pentraxin 3 (PTX3) is …
structure, pentraxins are divided into short and long pentraxin families. Pentraxin 3 (PTX3) is …
The role of pentraxins: From inflammation, tissue repair and immunity to biomarkers
Pentraxins are a superfamily of highly conserved molecules characterized by a common
structural motif, the so-called “pentraxin domain”(1, 2). C reactive protein (CRP), originally …
structural motif, the so-called “pentraxin domain”(1, 2). C reactive protein (CRP), originally …
Pentraxins in innate immunity: lessons from PTX3
The innate immune system constitutes the first line of defence against microorganisms and
plays a primordial role in the activation and regulation of adaptive immunity. The innate …
plays a primordial role in the activation and regulation of adaptive immunity. The innate …
The long pentraxin PTX3 as a key component of humoral innate immunity and a candidate diagnostic for inflammatory diseases
The innate immune system is composed of a cellular arm and a humoral arm. Components
of the humoral arm include members of the complement cascade and soluble pattern …
of the humoral arm include members of the complement cascade and soluble pattern …
Association of pentraxin 3 with autoimmune diseases: a systematic review and meta-analysis
X Huang, L Zhang, Y Duan, Y Wang, J Wang - Archives of medical …, 2016 - Elsevier
Background and Aims Pentraxin 3 (PTX3) plays an important role in the inflammatory
processes. Recently it has been reported to be involved in autoimmune diseases. Many …
processes. Recently it has been reported to be involved in autoimmune diseases. Many …
The long pentraxin PTX3 in vascular pathology
Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition
proteins characterized by a cyclic multimeric structure. Based on the primary structure of the …
proteins characterized by a cyclic multimeric structure. Based on the primary structure of the …
Pentraxins: multifunctional proteins at the interface of innate immunity and inflammation
L Deban, B Bottazzi, C Garlanda, YM de la Torre… - Biofactors, 2009 - Wiley Online Library
Pentraxins are a family of multimeric pattern recognition proteins highly conserved in
evolution. On the basis of the primary structure of the protomer, pentraxins are divided into …
evolution. On the basis of the primary structure of the protomer, pentraxins are divided into …
Pentraxins in innate immunity: from C-reactive protein to the long pentraxin PTX3
Pentraxins are a family of multimeric pattern-recognition proteins highly conserved in
evolution. Based on the primary structure of the subunit, the pentraxins are divided into two …
evolution. Based on the primary structure of the subunit, the pentraxins are divided into two …