Schizophrenia is a chronic and debilitating mental illness characterized by a broad range of
abnormal behaviors, including delusions and hallucinations, impaired cognitive function, as …

Multiple lines of evidence point to an involvement of white matter in schizophrenia.
Microarray data, white matter imaging techniques, ultrastructural studies, quantitative …

Imaging and postmortem studies have revealed disturbed oligodendroglia-related
processes in patients with schizophrenia and provided much evidence for disturbed …

Studies of genetics, serum cytokines, and autoimmune illnesses suggest that immune-
related abnormalities are involved in the disease process of schizophrenia. Furthermore …

Multiple lines of evidence in schizophrenia, from brain imaging, studies in postmortem
brains, and genetic association studies, have implicated oligodendrocyte and myelin …

Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …

Neuronal circuitry relies to a large extent on the presence of functional myelin produced in
the brain by oligodendrocytes. Schizophrenia has been proposed to arise partly from altered …

Microglial activation has been proposed to be involved in the pathophysiology of
schizophrenia (SCZ). We hypothesized that dystrophic alterations of oligodendrocytes …

BACKGROUND: Schizophrenia is a brain disease involving progressive loss of gray matter
of unknown cause. Most likely, this loss reflects neuronal damage, which should, in turn, be …

Oligodendrocyte genes and white matter tracts have been implicated in the pathophysiology
of schizophrenia and may play an important etiopathogenic role in cognitive dysfunction in …