Public concern on mental health has noticeably increased given the high prevalence of
neuropsychiatric disorders. Cognition and emotionality are the most affected functions in …

The endocannabinoid (eCB) system is a widespread intercellular signalling mechanism that
plays a critical role in body homoeostasis. It is located in key points involved in food intake …

Despite widespread evidence of endocannabinoid system involvement in the
pathophysiology of psychiatric disorders, our understanding remains rudimentary. Here we …

The high heterogeneity of psychiatric disorders leads to a lack of diagnostic precision.
Therefore, the search of biomarkers is a fundamental aspect in psychiatry to reach a more …

Mental disorders have a high prevalence compared with many other health conditions and
are the leading cause of disability worldwide. Several studies performed in the last years …

Mental disorders represent a significant public health burden worldwide due to their high
prevalence, chronically disabling nature, and substantial impact on quality of life. Despite …

G-protein-coupled receptor (GPCR)-mediated signalling is the most widely used signalling
mechanism in cells, and its regulation is important for various physiological functions. The …

Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric
disorders, including anxiety, psychosis, and depression. The mechanisms responsible for …

Depression is a common mental disorder and is the leading cause of suicide globally.
Because of the significant diversity in mental disorders, accurate diagnosis is difficult …

Cannabidiol (CBD) represents a new promising drug due to a wide spectrum of
pharmacological actions. In order to relate CBD clinical efficacy to its pharmacological …