Carboxylesterase (CES) 1 is the predominant esterase expressed in the human liver and is
capable of catalyzing the hydrolysis of a wide range of therapeutic agents, toxins, and …

Carboxylesterase (CES) 1 is the most abundant drug-metabolizing enzyme in human livers,
comprising approximately 1% of the entire liver proteome. CES1 is responsible for 80 …

ABSTRACT Introduction Carboxylesterase 1 (CES1) and carboxylesterase 2 (CES2) are
among the most abundant hydrolases in humans, catalyzing the metabolism of numerous …

Mammalian carboxylesterases (CES), the key members of the serine hydrolase superfamily,
hydrolyze a wide range of endogenous substances and xenobiotics bearing ester or amide …

Background: Carboxylesterases (CES) play a critical role in catalyzing hydrolysis of esters,
amides, carbamates and thioesters, as well as bioconverting prodrugs and soft drugs. The …

Carboxylesterase 1 (CES1) is the major hydrolase in human liver. The enzyme is involved in
the metabolism of several important therapeutic agents, drugs of abuse, and endogenous …

CES1 is involved in the hydrolysis of ester group-containing xenobiotic and endobiotic
compounds including several essential and commonly used drugs. The individual variation …

Background: Herbal products have grown steadily across the globe and have increasingly
been incorporated into western medicine for healthcare aims, thereby causing potential …

Mammalian carboxylesterases (CEs) are key enzymes from the serine hydrolase
superfamily. In the human body, two predominant carboxylesterases (CES1 and CES2) …

Mammalian carboxylesterases are key serine hydrolases that catalyze the hydrolysis of a
wide variety of ester compounds in the corresponding carboxylic acids and alcohols. In …