The tobacco smoke component, acrolein, as a major culprit in lung diseases and respiratory cancers: Molecular mechanisms of acrolein cytotoxic activity
P Hikisz, D Jacenik - Cells, 2023 - mdpi.com
Acrolein, a highly reactive unsaturated aldehyde, is a ubiquitous environmental pollutant
that seriously threatens human health and life. Due to its high reactivity, cytotoxicity and …
that seriously threatens human health and life. Due to its high reactivity, cytotoxicity and …
Acrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary disease
N Moretto, G Volpi, F Pastore… - Annals of the New York …, 2012 - Wiley Online Library
Acrolein (2‐propenal) is a highly reactive α, β‐unsaturated aldehyde and a respiratory
irritant that is ubiquitously present in the environment but that can also be generated …
irritant that is ubiquitously present in the environment but that can also be generated …
Acrolein–a pulmonary hazard
K Bein, GD Leikauf - Molecular nutrition & food research, 2011 - Wiley Online Library
Acrolein is a respiratory irritant that can be generated during cooking and is in
environmental tobacco smoke. More plentiful in cigarette smoke than polycyclic aromatic …
environmental tobacco smoke. More plentiful in cigarette smoke than polycyclic aromatic …
Biomarkers of chronic acrolein inhalation exposure in mice: implications for tobacco product-induced toxicity
DJ Conklin, MV Malovichko, I Zeller… - Toxicological …, 2017 - academic.oup.com
Exposure to tobacco smoke, which contains several harmful and potentially harmful
constituents such as acrolein increases cardiovascular disease (CVD) risk. Although high …
constituents such as acrolein increases cardiovascular disease (CVD) risk. Although high …
Acrolein induced both pulmonary inflammation and the death of lung epithelial cells
Acrolein, a compound found in cigarette smoke, is a major risk factor for respiratory
diseases. Previous research determined that both acrolein and cigarette smoke produced …
diseases. Previous research determined that both acrolein and cigarette smoke produced …
Acrolein-induced cytotoxicity in cultured human bronchial epithelial cells. Modulation by alpha-tocopherol and ascorbic acid
M Nardini, EI Finkelstein, S Reddy, G Valacchi… - Toxicology, 2002 - Elsevier
Acrolein is a highly reactive unsaturated hazardous air pollutant of human health concern,
particularly as a component of cigarette smoke. In this study, the mechanisms of acrolein …
particularly as a component of cigarette smoke. In this study, the mechanisms of acrolein …
Quantitative Liquid Chromatography–Nanoelectrospray Ionization–High-Resolution Tandem Mass Spectrometry Analysis of Acrolein-DNA Adducts and Etheno-DNA …
Cigarette smoking is an important source of human exposure to toxicants and carcinogens
and contributes significantly to cancer morbidity and mortality worldwide. Acrolein, a …
and contributes significantly to cancer morbidity and mortality worldwide. Acrolein, a …
Molecular mechanisms of acrolein toxicity: relevance to human disease
A Moghe, S Ghare, B Lamoreau… - Toxicological …, 2015 - academic.oup.com
Acrolein, a highly reactive unsaturated aldehyde, is a ubiquitous environmental pollutant
and its potential as a serious environmental health threat is beginning to be recognized …
and its potential as a serious environmental health threat is beginning to be recognized …
Inhibition of neutrophil apoptosis by acrolein: a mechanism of tobacco-related lung disease?
EI Finkelstein, M Nardini… - American Journal of …, 2001 - journals.physiology.org
Cigarette smoking is known to contribute to inflammatory diseases of the respiratory tract by
promoting recruitment of inflammatory-immune cells such as neutrophils and perhaps by …
promoting recruitment of inflammatory-immune cells such as neutrophils and perhaps by …
Acrolein induces endoplasmic reticulum stress and causes airspace enlargement
Y Kitaguchi, L Taraseviciene-Stewart, M Hanaoka… - PloS one, 2012 - journals.plos.org
Background Given the relative abundance and toxic potential of acrolein in inhaled cigarette
smoke, it is surprising how little is known about the pulmonary and systemic effects of …
smoke, it is surprising how little is known about the pulmonary and systemic effects of …
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