Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains
SS Moy, JJ Nadler, NB Young, A Perez… - Behavioural brain …, 2007 - Elsevier
Three defining clinical symptoms of autism are aberrant reciprocal social interactions,
deficits in social communication, and repetitive behaviors, including motor stereotypies and …
deficits in social communication, and repetitive behaviors, including motor stereotypies and …
Assessing autism-like behavior in mice: variations in social interactions among inbred strains
VJ Bolivar, SR Walters, JL Phoenix - Behavioural brain research, 2007 - Elsevier
Autism is a pervasive developmental disorder, with characteristics including impairments in
reciprocal social interaction, impaired communication, and repetitive/stereotyped behaviors …
reciprocal social interaction, impaired communication, and repetitive/stereotyped behaviors …
Social approach and repetitive behavior in eleven inbred mouse strains
SS Moy, JJ Nadler, NB Young, RJ Nonneman… - Behavioural brain …, 2008 - Elsevier
Core symptoms of autism include deficits in social interaction, impaired communication, and
restricted, repetitive behaviors. The repetitive behavior domain encompasses abnormal …
restricted, repetitive behaviors. The repetitive behavior domain encompasses abnormal …
Sociability and preference for social novelty in five inbred strains: an approach to assess autistic‐like behavior in mice
SS Moy, JJ Nadler, A Perez, RP Barbaro… - Genes, Brain and …, 2004 - Wiley Online Library
Deficits in social interaction are important early markers for autism and related
neurodevelopmental disorders with strong genetic components. Standardized behavioral …
neurodevelopmental disorders with strong genetic components. Standardized behavioral …
Mouse models of autism spectrum disorders: the challenge for behavioral genetics
SS Moy, JJ Nadler, TR Magnuson… - American Journal of …, 2006 - Wiley Online Library
Autism is a severe neurodevelopmental disorder, which typically emerges early in
childhood. The core symptoms of autism include deficits in social interaction, impaired …
childhood. The core symptoms of autism include deficits in social interaction, impaired …
Low sociability in BTBR T+ tf/J mice is independent of partner strain
Inbred mouse strains differ greatly in social behaviors, making them a valuable resource to
study genetic and non-genetic mechanisms underlying social deficits relevant to autism …
study genetic and non-genetic mechanisms underlying social deficits relevant to autism …
Mouse behavioral assays relevant to the symptoms of autism
JN Crawley - Brain pathology, 2007 - Wiley Online Library
While the cause of autism remains unknown, the high concordance between monozygotic
twins supports a strong genetic component. The importance of genetic factors in autism …
twins supports a strong genetic component. The importance of genetic factors in autism …
BALB/c mice: low sociability and other phenotypes that may be relevant to autism
ES Brodkin - Behavioural brain research, 2007 - Elsevier
Low sociability is one of the most prominent and disabling symptoms of autism. The biology
of sociability is not well understood, and there is no available treatment that adequately …
of sociability is not well understood, and there is no available treatment that adequately …
Autism‐like behavioral phenotypes in BTBR T+ tf/J mice
HG McFarlane, GK Kusek, M Yang… - Genes, Brain and …, 2008 - Wiley Online Library
Autism is a behaviorally defined neurodevelopmental disorder of unknown etiology. Mouse
models with face validity to the core symptoms offer an experimental approach to test …
models with face validity to the core symptoms offer an experimental approach to test …
Colony formation of C57BL/6J mice in visible burrow system: identification of eusocial behaviors in a background strain for genetic animal models of autism
H Arakawa, DC Blanchard, RJ Blanchard - Behavioural brain research, 2007 - Elsevier
Deficits in social interaction are primary characteristics of autism, which has strong genetic
components. Genetically manipulated mouse models may provide a useful research tool to …
components. Genetically manipulated mouse models may provide a useful research tool to …