[HTML][HTML] HLH as an additional warning sign of inborn errors of immunity beyond familial-HLH in children: a systematic review
S Ricci, WM Sarli, L Lodi, C Canessa, F Lippi… - Frontiers in …, 2024 - frontiersin.org
Background Hemophagocytic Lymphohistiocytosis (HLH) is a rare and life-threatening
condition characterized by a severe impairment of the immune homeostasis. While Familial …
condition characterized by a severe impairment of the immune homeostasis. While Familial …
Dilemmas in diagnosis and management of hemophagocytic lymphohistiocytosis in children
XJ Xu, YM Tang - World Journal of Pediatrics, 2020 - Springer
Background Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening entity which is
characterized by severe hyperinflammation. Now the HLH-2004 protocol has been widely …
characterized by severe hyperinflammation. Now the HLH-2004 protocol has been widely …
[HTML][HTML] Presentations and outcomes of familial hemophagocytic lymphohistiocytosis in the pediatric intensive care units (PICUs)
F Alsohime, MH Temsah, RM Alotaibi… - Frontiers in …, 2023 - frontiersin.org
Objectives: We aimed to describe Familial Hemophagocytic Lymphohistiocytosis (F-HLH)
patients' clinical features, intensive care courses, and outcomes. Methods: Multi-center …
patients' clinical features, intensive care courses, and outcomes. Methods: Multi-center …
[HTML][HTML] Pathogenic gene mutations or variants identified by targeted gene sequencing in adults with hemophagocytic lymphohistiocytosis
Y Miao, HY Zhu, C Qiao, Y Xia, Y Kong… - Frontiers in …, 2019 - frontiersin.org
Hemophagocytic lymphohistiocytosis (HLH) can be classified into primary HLH and
secondary HLH. Primary HLH usually occurs in infants and children with an underlying …
secondary HLH. Primary HLH usually occurs in infants and children with an underlying …
[HTML][HTML] Simple evaluation of clinical situation and subtypes of pediatric hemophagocytic lymphohistiocytosis by cytokine patterns
XJ Xu, ZB Luo, H Song, WQ Xu, JI Henter… - Frontiers in …, 2022 - frontiersin.org
Background Hemophagocytic lymphohistiocytosis (HLH) is a rapidly fatal disease caused by
immune dysregulation. Early initiation of treatment is imperative for saving lives. However, a …
immune dysregulation. Early initiation of treatment is imperative for saving lives. However, a …
An overview of hemophagocytic lymphohistiocytosis
YM Esteban, JLO de Jong, MS Tesher - Pediatric annals, 2017 - journals.healio.com
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome characterized by
a dysregulated hyperinflammatory response associated with aberrant activation of …
a dysregulated hyperinflammatory response associated with aberrant activation of …
A hungry Histiocyte, altered immunity and myriad of problems: Diagnostic challenges for Pediatric HLH
Introduction Hemophagocytic lymphohistiocytosis (HLH) is an immune deregulation disorder
with varied clinical presentation which clinically overlaps with widespread tropical infections …
with varied clinical presentation which clinically overlaps with widespread tropical infections …
Clinical features and diagnosis of hemophagocytic lymphohistiocytosis
KL McClain, O Eckstein - UpToDate, 2018 - uptodate.com
Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life-threatening syndrome
of excessive immune activation. It most frequently affects infants from birth to 18 months of …
of excessive immune activation. It most frequently affects infants from birth to 18 months of …
Hemophagocytic Lymphohistiocytosis
H Major-Monfried, S Friedman, S Moerdler - 2022 - publications.aap.org
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of extreme, systemic immune
activation characterized by prolonged fever, hepatosplenomegaly, cytopenias, and elevated …
activation characterized by prolonged fever, hepatosplenomegaly, cytopenias, and elevated …
Challenges in the diagnosis and management of pediatric hemophagocytic lymphohistiocytosis
Hemophagocytic lymphohistiocytosis (HLH) is a multiorgan syndrome resulting from
defective regulation of inflammation in which excessive activation of macrophages and …
defective regulation of inflammation in which excessive activation of macrophages and …