Certain drugs and chemicals, such as chloroquine, chlorpromazine, and 1‐methyl‐4‐phenyl‐
1, 2, 3, 6‐tetrahydropyridine (MPTP), are bound to melanin and retained in pigment cells for …

Certain drugs with melanin affinity are known to have caused pigmentary lesions in the eye
and skin. This was the basis for the hypothesis that compounds with melanin affinity may …

Various drugs and other chemicals, such as organic amines, metals, polycyclic aromatic
hydrocarbons, etc., are bound to melanin and retained in pigmented tissues for long periods …

Within both the pharmaceutical industry and various drug regulatory authorities, there has
been a growing interest in and awareness of the comparatively recent realization of the …

The function of neuromelanin is not known, but some properties of the pigment suggest a
protective action. Its unique ability to accumulate and retain several compounds, such as …

The color of hair, skin, and eyes in animals mainly depends on the quantity, quality, and
distribution of the pigment melanin, which occurs in two types: black to brown eumelanin …

The antimalarial agent chloroquine is known for high affinity for melanin. This 4‐
aminoquinoline derivative was examined for anti‐melanoma activity and uptake into …

Melanin is a dark biological pigment found throughout nature. It is a predominantly indolic
macromolecule [1], although the name conveys no chemical information, and means simply …

The function of the dark polymer pigment neuromelanin found in catecholaminergic neurons
of the human brain is not understood, especially as most published data are based upon a …

Melanin is a polyanionic pigment that colors, eg, the hair, skin and eyes. The pigment
neuromelanin is closely related to melanin and is mainly produced in specific neurons of the …