Streptococcus pneumoniae is a leading cause of infectious disease globally.
Nasopharyngeal colonization occurs in biofilms and precedes infection. Prior studies have …

Streptococcus pneumoniae is a common human nasopharyngeal commensal colonizing
10% to 40% of healthy individuals, depending on age. Despite a low invasive disease rate …

Influenza and other respiratory viral infections are the most common type of acute respiratory
infection. Viral infections predispose patients to secondary bacterial infections, which often …

It is unclear whether Streptococcus pneumoniae in biofilms are virulent and contribute to
development of invasive pneumococcal disease (IPD). Using electron microscopy we …

Streptococcus pneumoniae is the dominant cause of community-acquired pneumonia
worldwide. Invasion of the pleural space is common and results in increased mortality. We …

Streptococcus pneumoniae (the pneumococcus) is a common colonizer of the human
nasopharynx. Despite a low rate of invasive disease, the high prevalence of colonization …

Staphylococcus aureus is a ubiquitous opportunistic human pathogen and a major health
concern worldwide, causing a wide variety of diseases from mild skin infections to systemic …

Streptococcus pneumoniae accounts for a significant global burden of morbidity and
mortality and biofilm development is increasingly recognised as important for colonization …

Influenza A virus (IAV)-related mortality is often due to secondary bacterial infections,
primarily by pneumococci. Here, we study how IAV-modulated changes in the lungs affect …

Streptococcus pneumoniae is an opportunistic pathogen that colonizes the nasopharynx.
Herein we show that carbon availability is distinct between the nasopharynx and …