The association of genetic variation with disease and drug response, and improvements in
nucleic acid technologies, have given great optimism for the impact of 'genomic medicine' …

The human genome is arguably the most complete mammalian reference assembly,,, yet
more than 160 euchromatic gaps remain,, and aspects of its structural variation remain …

The end of the start for population sequencing | Nature Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Recent advances in high-throughput DNA sequencing technologies have enabled order-of-
magnitude improvements in both cost and throughput. Here we report the use of single …

Recent advances in whole-genome sequencing have brought the vision of personal
genomics and genomic medicine closer to reality. However, current methods lack clinical …

The decade since the Human Genome Project ended has witnessed a remarkable
sequencing technology explosion that has permitted a multitude of questions about the …

Here we present the first diploid genome sequence of an Asian individual. The genome was
sequenced to 36-fold average coverage using massively parallel sequencing technology …

This review commemorates the 40th anniversary of DNA sequencing, a period in which we
have already witnessed multiple technological revolutions and a growth in scale from a few …

An enormous amount of genetic sequence data has been obtained with gel-based DNA
sequencing methods [HN1]. To understand the function of the genes and their health …

Recent advances in sequencing technologies have initiated an era of personal genome
sequences. To date, human genome sequences have been reported for individuals with …