Metastatic complications are responsible for more than 90% of cancer-related deaths. The
progression from an isolated tumor to disseminated metastatic disease is a multistep …

The extracellular matrix (ECM) is essential for cell support during homeostasis and plays a
critical role in cancer. Although research often concentrates on the tumor's cellular aspect …

The main cause of cancer-related mortality, metastasis, is a complex, multi-step process.
The extracellular matrix (ECM) component of solid tumors has been implicated in metastatic …

Simple Summary This review takes the extracellular matrix (ECM) as the starting point, and
describes its influence and related mechanisms on the biological behavior of pancreatic …

Tumor extracellular matrix (ECM) operates in a coordinated mode with cancer and stroma
cells to evoke the multistep process of metastatic potential. The remodeled tumor-associated …

The tumor microenvironment (TME) is composed of various cell types embedded in an
altered extracellular matrix (ECM). ECM not only serves as a support for tumor cell but also …

Extracellular matrix (ECM) is an essential component of the tumor microenvironment.
Cancer development and progression are associated with increased ECM deposition and …

The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …

Simple Summary The extracellular matrix (ECM) has emerged as a critical part of the tumor
microenvironment. This glycoprotein-and proteoglycan-rich part of the tumor serves as a …

The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …