Mathematical models, which are based on a firm understanding of biological interactions,
can provide nonintuitive insights into the dynamics of host responses to infectious agents …

During the past 6 years, there have been substantial advances in our understanding of
human immunodeficiency virus 1 and other viruses, such as hepatitis B virus and hepatitis C …

Over the last few decades, in-host mathematical modeling has increasingly been used in
attempts to understand the pathogenesis of numerous viruses such as hepatitis B virus …

This groundbreaking book describes the emerging field of theoretical immunology, in
particular the use of mathematical models to describe the spread of infectious diseases …

Primary human immunodeficiency virus (HIV) infection is characterized by an initial
exponential increase of viral load in peripheral blood reaching a peak, followed by a rapid …

The recent development of potent antiviral drugs not only has raised hopes for effective
treatment of infections with HIV or the hepatitis B virus, but also has led to important …

We analyse mathematical models comparing thein vivodynamics of macrophage-and T cell
infection by HIV. Experiments suggest that HIV can only replicate in activated T cells …

Earlier models of virus evolution during single infections do not include target cell limitation.
Here we extend the basic mathematical framework of these theories and study the effect of …

We investigate possible interactions between HIV and other pathogens that would arise if
HIV replication were enhanced by the activation of T helper cells specific to other pathogens …

We explore how an infected cell's virion production rate can affect the relative fitness of a
virus within a host. We perform an invasion analysis, based on an age-structured model of …