Population dynamics of immune responses to persistent viruses
MA Nowak, CRM Bangham - Science, 1996 - science.org
Mathematical models, which are based on a firm understanding of biological interactions,
can provide nonintuitive insights into the dynamics of host responses to infectious agents …
can provide nonintuitive insights into the dynamics of host responses to infectious agents …
Modelling viral and immune system dynamics
AS Perelson - Nature reviews immunology, 2002 - nature.com
During the past 6 years, there have been substantial advances in our understanding of
human immunodeficiency virus 1 and other viruses, such as hepatitis B virus and hepatitis C …
human immunodeficiency virus 1 and other viruses, such as hepatitis B virus and hepatitis C …
[PDF][PDF] Analytical solution for an in-host viral infection model with time-inhomogeneous rates
Y Shang - Acta Phys. Pol. B, 2015 - researchgate.net
Over the last few decades, in-host mathematical modeling has increasingly been used in
attempts to understand the pathogenesis of numerous viruses such as hepatitis B virus …
attempts to understand the pathogenesis of numerous viruses such as hepatitis B virus …
[图书][B] Virus dynamics: mathematical principles of immunology and virology: mathematical principles of immunology and virology
This groundbreaking book describes the emerging field of theoretical immunology, in
particular the use of mathematical models to describe the spread of infectious diseases …
particular the use of mathematical models to describe the spread of infectious diseases …
Mathematical modeling of viral kinetics under immune control during primary HIV-1 infection
Primary human immunodeficiency virus (HIV) infection is characterized by an initial
exponential increase of viral load in peripheral blood reaching a peak, followed by a rapid …
exponential increase of viral load in peripheral blood reaching a peak, followed by a rapid …
Virus dynamics and drug therapy
The recent development of potent antiviral drugs not only has raised hopes for effective
treatment of infections with HIV or the hepatitis B virus, but also has led to important …
treatment of infections with HIV or the hepatitis B virus, but also has led to important …
Dynamics of macrophage and T cell infection by HIV
We analyse mathematical models comparing thein vivodynamics of macrophage-and T cell
infection by HIV. Experiments suggest that HIV can only replicate in activated T cells …
infection by HIV. Experiments suggest that HIV can only replicate in activated T cells …
Virus dynamics: the effect of target cell limitation and immune responses on virus evolution
Earlier models of virus evolution during single infections do not include target cell limitation.
Here we extend the basic mathematical framework of these theories and study the effect of …
Here we extend the basic mathematical framework of these theories and study the effect of …
Models of interactions between HIV and other pathogens
We investigate possible interactions between HIV and other pathogens that would arise if
HIV replication were enhanced by the activation of T helper cells specific to other pathogens …
HIV replication were enhanced by the activation of T helper cells specific to other pathogens …
Optimizing within-host viral fitness: infected cell lifespan and virion production rate
We explore how an infected cell's virion production rate can affect the relative fitness of a
virus within a host. We perform an invasion analysis, based on an age-structured model of …
virus within a host. We perform an invasion analysis, based on an age-structured model of …