Early and profound pathological changes are evident in the locus coeruleus (LC) in
dementia and Parkinson's disease, with effects on arousal, attention, cognitive and motor …

Locus Coeruleus (LC) is the main noradrenergic nucleus of the brain, which is involved in
many physiological functions including cognition; its impairment may be crucial in the …

The locus coeruleus (LC), the major origin of noradrenergic modulation of the central
nervous system, may play an important role in neuropsychiatric disorders including …

The locus coeruleus (LC) is a brainstem nucleus involved in important cognitive functions.
Recent developments in neuroimaging methods and scanning protocols have made it …

The locus coeruleus (LC) has long been underappreciated for its role in the pathophysiology
of Alzheimer's disease (AD), Parkinson's disease (PD), and other neurodegenerative …

The locus coeruleus (LC), a major origin of noradrenergic projections in the central nervous
system (CNS), may serve a critical role in the pathogenesis of neurodegenerative disorders …

Locus Coeruleus (LC) is a neuromelanin-rich brainstem structure that is the source of
noradrenaline in the cortex and is thought to modulate attention and memory. LC imaging in …

The locus coeruleus (LC) is involved in numerous crucial brain functions and several
disorders like depression and Alzheimer's disease. Recently, the LC resting‐state functional …

The locus coeruleus (LC), the major origin of noradrenergic modulation of the central
nervous system, innervates extensive areas throughout the brain and is implicated in a …

There is growing evidence that neuronal integrity of the noradrenergic locus coeruleus (LC)
is important for later-life cognition. Less understood is how LC integrity relates to brain …