[HTML][HTML] Bacterial vaccines in clinical and preclinical development 2021: an overview and analysis

World Health Organization - 2022 - books.google.com
Page 1 Bacterial vaccines in clinical and preclinical development 2021 An overview and analysis
World Health Organization Page 2 Bacterial vaccines in clinical and preclinical development 2021 …

Vaccine renaissance

JW Almond - Nature Reviews Microbiology, 2007 - go.gale.com
Vaccines are one of the most useful and cost-effective tools for reducing the morbidity and
mortality that are associated with infectious diseases. Here, Jeffrey Almond discusses the …

Genome-based bacterial vaccines: current state and future outlook

A Schubert-Unkmeir, M Christodoulides - BioDrugs, 2013 - Springer
Genome-based reverse vaccinology (RV) is a multi-step experimental strategy which starts
from in silico analysis of whole genome sequences, from which vaccine candidates can be …

Challenges for clinical development of vaccines for prevention of hospital-acquired bacterial infections

I Bekeredjian-Ding - Frontiers in immunology, 2020 - frontiersin.org
Increasing antibiotic resistance in bacteria causing endogenous infections has entailed a
need for innovative approaches to therapy and prophylaxis of these infections and raised a …

Developing antibacterial vaccines in genomics and proteomics era

DK Kaushik, D Sehgal - Scandinavian journal of immunology, 2008 - Wiley Online Library
Infectious diseases are the greatest cause of global morbidity and mortality. About half of this
burden is caused by pathogenic bacteria. One of the most effective ways to prevent …

Recombinant vaccines in 2022: a perspective from the cell factory

MT de Pinho Favaro, J Atienza-Garriga… - Microbial cell …, 2022 - Springer
The last big outbreaks of Ebola fever in Africa, the thousands of avian influenza outbreaks
across Europe, Asia, North America and Africa, the emergence of monkeypox virus in …

Vaccine evolution and its application to fight modern threats

E Andreano, U D'Oro, R Rappuoli, O Finco - Frontiers in immunology, 2019 - frontiersin.org
Before the development of the first vaccine, infectious diseases were a major cause of death
around the globe with life expectancy estimated to be< 50 years. Three measures have …

Vaccine Development against Infectious Diseases: State of the Art, New Insights, and Future Directions

F Conceição Silva, PM De Luca, JC Lima-Junior - Vaccines, 2023 - mdpi.com
In the 18th century, English physician Edward Jenner laid the foundation for modern
vaccination by achieving protection against variola. His observations led to the development …

Vaccine safety: myths and misinformation

S Geoghegan, KP O'Callaghan, PA Offit - Frontiers in microbiology, 2020 - frontiersin.org
The World Health Organization has named vaccine hesitancy as one of the top ten threats to
global health in 2019. The reasons why people choose not to vaccinate are complex, but …

The role of bacterial vaccines in the fight against antimicrobial resistance: an analysis of the preclinical and clinical development pipeline

I Frost, H Sati, P Garcia-Vello… - The Lancet …, 2023 - thelancet.com
Vaccines can be highly effective tools in combating antimicrobial resistance as they reduce
infections caused by antibiotic-resistant bacteria and antibiotic consumption associated with …