A multicomponent vaccine provides Immunity against local and systemic infections by group a Streptococcus across serotypes

S Bi, M Xu, Y Zhou, X Xing, A Shen, B Wang - MBio, 2019 - Am Soc Microbiol
Group A streptococcus (GAS) species are responsible for a broad spectrum of human
diseases, ranging from superficial to invasive infections, and are associated with …

Recent Scientific Advancements towards a Vaccine against Group A Streptococcus

J Fan, I Toth, RJ Stephenson - Vaccines, 2024 - mdpi.com
Group A Streptococcus (GAS), or Streptococcus pyogenes, is a gram-positive bacterium that
extensively colonises within the human host. GAS is responsible for causing a range of …

A brief review on Group A Streptococcus pathogenesis and vaccine development

SA Castro, HC Dorfmueller - Royal Society open science, 2021 - royalsocietypublishing.org
Streptococcus pyogenes, also known as Group A Streptococcus (GAS), is a Gram-positive
human-exclusive pathogen, responsible for more than 500 000 deaths annually worldwide …

Moving forward: a mucosal vaccine against group A streptococcus

MM Georgousakis, DJ McMillan, MR Batzloff… - Expert review of …, 2009 - Taylor & Francis
Streptococcus pyogenes, commonly referred to as group A streptococcus (GAS), colonizes
the epithelial surfaces of the upper respiratory tract and the skin, where it causes a myriad of …

[HTML][HTML] Group A Streptococcus Infections: Their Mechanisms, Epidemiology, and Current Scope of Vaccines

V Iyer, V Sagar, D Toor, V Lyngdoh, G Nongrum… - Cureus, 2022 - ncbi.nlm.nih.gov
Group A streptococci (GAS) are gram-positive, cocci-shaped bacteria that cause a wide
variety of infections and are a cause of significant health burden, particularly in lower-and …

Disease manifestations and pathogenic mechanisms of group A Streptococcus

MJ Walker, TC Barnett, JD McArthur… - Clinical microbiology …, 2014 - Am Soc Microbiol
Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …

Vaccine development for group a streptococcus infections and associated diseases

MR Batzloff, KS Sriprakash, MF Good - Current Drug Targets, 2004 - ingentaconnect.com
Group A streptococcus (GAS) is responsible for a number of diseases ranging from
uncomplicated pharyngitis through to life-treating invasive and post-infectious diseases such …

[HTML][HTML] Mucosal Immunization Has Benefits over Traditional Subcutaneous Immunization with Group A Streptococcus Antigens in a Pilot Study in a Mouse Model

HA Shaw, A Remmington, G McKenzie, C Winkel… - Vaccines, 2023 - mdpi.com
Group A Streptococcus (GAS) is a major human pathogen for which there is no licensed
vaccine. To protect against infection, a strong systemic and mucosal immune response is …

Progress in development of group A streptococcus vaccines

Y Song, X Zhang, C Lu, F Zhang… - Current pharmaceutical …, 2013 - ingentaconnect.com
Streptococcus pyogenes or Group A Streptococcus (GAS) is a major Gram-positive human
pathogen that causes diverse human diseases with a high morbidity and mortality …

[HTML][HTML] The quest for GAS vaccine

M Pandey, MF Good - Oncotarget, 2015 - ncbi.nlm.nih.gov
The pursuit of a safe vaccine against Streptococcus pyogenes (group A streptococcus, GAS)
that does not induce autoimmune pathology and that affords coverage for most GAS …