Deciphering the role and the mechanism of B-cell Non-Hodgkin Lymphoma-derived small Extracellular Vesicles in modulating the phenotype of myeloid cells.

M Bordas - 2023 - archiv.ub.uni-heidelberg.de
Non-Hodgkin Lymphomas (NHL) represent one of the most common cancers worldwide.
Among the most common forms of NHL are found Chronic Lymphocytic Leukemia (CLL) …

[HTML][HTML] Analysis of CD20 and PD-L1 levels on small extracellular vesicles (sEV) produced by DLBCL cells and EBV-transformed B cells, and potential role in T cell …

H Akil, H Bentayeb, M Aitamer, C Vignoles… - … Hematology & Oncology, 2024 - Springer
Increasing evidence supports a role for small extracellular vesicles (sEV, including
exosomes) in Diffuse Large B-cell lymphoma (DLBCL) progression and resistance to …

Extracellular vesicles in DLBCL provide abundant clues to aberrant transcriptional programming and genomic alterations

SC Rutherford, AA Fachel, S Li, S Sawh… - Blood, The Journal …, 2018 - ashpublications.org
The biological role of extracellular vesicles (EVs) in diffuse large B-cell lymphoma (DLBCL)
initiation and progression remains largely unknown. We characterized EVs secreted by 5 …

Small extracellular vesicles: multi-faceted tools for leukemia immune evasion in vivo

E Gargiulo, E Viry, E Moussay, J Paggetti - Oncoimmunology, 2022 - Taylor & Francis
Recently, small extracellular vesicles (sEVs) secreted in vivo from chronic lymphocytic
leukemia (CLL) preclinical murine models were characterized. Leukemia microenvironment …

Diffuse large B cell lymphoma‐derived extracellular vesicles educate macrophages to promote tumours progression by increasing PGC‐1β

W Liu, M Zhu, H Wang, W Wang… - Scandinavian Journal of …, 2020 - Wiley Online Library
Tumour‐associated macrophages (TAMs) comprise an important part of the tumour
microenvironment and play a key role in malignant tumours progression. Tumour‐derived …

[HTML][HTML] Tumor-derived small extracellular vesicles induce pro-inflammatory cytokine expression and PD-L1 regulation in M0 macrophages via IL-6/STAT3 and TLR4 …

M Pucci, S Raimondo, O Urzì, M Moschetti… - International Journal of …, 2021 - mdpi.com
Tumor-associated macrophages play a key role in promoting tumor progression by exerting
an immunosuppressive phenotype associated with the expression of programmed cell death …

[HTML][HTML] Extracellular vesicles: new players in lymphomas

V Navarro-Tableros, Y Gomez, G Camussi… - International journal of …, 2018 - mdpi.com
Lymphomas are heterogeneous diseases, and the term includes a number of histological
subtypes that are characterized by different clinical behavior and molecular phenotypes …

Extracellular vesicles released by CD40/IL-4–stimulated CLL cells confer altered functional properties to CD4+ T cells

DT Smallwood, B Apollonio, S Willimott… - Blood, The Journal …, 2016 - ashpublications.org
The complex interplay between cancer cells, stromal cells, and immune cells in the tumor
microenvironment (TME) regulates tumorigenesis and provides emerging targets for …

CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles

M Aitamer, H Akil, C Vignoles, M Branchaud… - British Journal of …, 2021 - nature.com
Background Small extracellular vesicles (sEVs) including exosomes, carrying the CD20,
could be involved in immunotherapy resistance in diffuse large B cell lymphoma (DLBCL) …

[HTML][HTML] The multifaceted roles of extracellular vesicles for therapeutic intervention with non-Hodgkin lymphoma

AA Lee, AK Godwin, H Abdelhakim - Extracellular Vesicles and …, 2024 - oaepublish.com
Extracellular vesicles (EVs) contribute to the development of cancer in various ways. Non-
Hodgkin lymphoma (NHL) is a cancer of mature lymphocytes and the most common …