Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus

H Jiao, Z Yan, X Zhai, Y Yang, N Wang, X Li… - Journal of …, 2023 - Am Soc Microbiol
Alphaviruses are emerging and re-emerging viruses that cause severe disease and threaten
public health worldwide. To advance the understanding of the underlying mechanisms of …

[HTML][HTML] The host transcriptome change involved in the inhibitory effect of exogenous interferon-γ on Getah virus replication

J Li, X Gao, X Liu, T Wu, H Song, W Gao, H Jia… - Frontiers in …, 2023 - frontiersin.org
Introduction Getah virus (GETV) has become a growing potential threat to the global
livestock industry and public health. However, little is known about the viral pathogenesis …

Attenuation of Getah virus by a single amino acid substitution at residue 253 of the E2 protein that might be part of a new heparan sulfate binding site on alphaviruses

N Wang, X Zhai, X Li, Y Wang, WT He, Z Jiang… - Journal of …, 2022 - Am Soc Microbiol
The emergence of new epidemic variants of alphaviruses poses a public health risk. It is
associated with adaptive mutations that often cause increased pathogenicity. Getah virus …

[HTML][HTML] Construction and characterization of a full-length infectious clone of Getah virus in vivo

T Ren, X Min, Q Mo, Y Wang, H Wang, Y Chen… - Virologica Sinica, 2022 - Elsevier
Getah virus (GETV) is a mosquito-borne virus of the genus Alphavirus in the family
Togaviridae and, in recent years, it has caused several outbreaks in animals. The molecular …

[HTML][HTML] TRIM5α promotes ubiquitination of RTA from epstein–barr virus to attenuate lytic progression

HH Huang, CS Chen, WH Wang, SW Hsu… - Frontiers in …, 2017 - frontiersin.org
Replication and transcription activator (Rta), a key protein expressed by Epstein–Barr virus
(EBV) during the immediate-early stage of the lytic cycle, is responsible for the activation of …

Origin, genetic diversity, adaptive evolution and transmission dynamics of Getah virus

N Shi, X Zhu, X Qiu, X Cao, Z Jiang… - Transboundary and …, 2022 - Wiley Online Library
As a member of the Alphavirus, Getah virus (GETV) was becoming more serious and posing
a serious threat to animal safety and public health. However, the circulation, distribution and …

[HTML][HTML] Trim28 acts as restriction factor of prototype foamy virus replication by modulating H3K9me3 marks and destabilizing the viral transactivator Tas

P Yuan, J Yan, S Wang, Y Guo, X Xi, S Han, J Yin… - Retrovirology, 2021 - Springer
Background Prototype foamy virus (PFV) is nonpathogenic complex retroviruses that
express a transcriptional transactivator Tas, which is essential for the activity of viral long …

Identifying the cellular interactome of Epstein-Barr virus lytic regulator Zta reveals cellular targets contributing to viral replication

Y Zhou, K Heesom, K Osborn, R AlMohammed… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT The human gammaherpesvirus Epstein-Barr virus (EBV)(human herpesvirus 4
[HHV4]) infects most adults and is an important contributor to the development of many types …

[HTML][HTML] Structure of infective Getah virus at 2.8 Å resolution determined by cryo-electron microscopy

A Wang, F Zhou, C Liu, D Gao, R Qi, Y Yin, S Liu… - Cell Discovery, 2022 - nature.com
Getah virus (GETV), a member of the genus alphavirus, is a mosquito-borne pathogen that
can cause pyrexia and reproductive losses in animals. Although antibodies to GETV have …

[HTML][HTML] Genome-wide RNAi screen identifies novel host proteins required for alphavirus entry

YS Ooi, KM Stiles, CY Liu, GM Taylor… - PLoS pathogens, 2013 - journals.plos.org
The enveloped alphaviruses include important and emerging human pathogens such as
Chikungunya virus and Eastern equine encephalitis virus. Alphaviruses enter cells by …