[HTML][HTML] Effect of tumor microenvironment on pathogenesis of the head and neck squamous cell carcinoma: a systematic review

B Peltanova, M Raudenska, M Masarik - Molecular cancer, 2019 - Springer
The tumor microenvironment (TME) is comprised of many different cell populations, such as
cancer-associated fibroblasts and various infiltrating immune cells, and non-cell …

[HTML][HTML] Tumor microenvironment in head and neck squamous cell carcinoma: Functions and regulatory mechanisms

G Wang, M Zhang, M Cheng, X Wang, K Li, J Chen… - Cancer letters, 2021 - Elsevier
The tumor microenvironment has been recently reported to play a pivotal role in sustaining
tumor cells survival and protecting them from immunotherapy and chemotherapy-induced …

[HTML][HTML] The tumor microenvironment contribution to development, growth, invasion and metastasis of head and neck squamous cell carcinomas

S Koontongkaew - Journal of Cancer, 2013 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinoma (HNSCC) is a complex tissue that contains tumor
cells and the surrounding stroma, which is populated by different types of mesenchymal …

[HTML][HTML] The head and neck squamous cell carcinoma microenvironment as a potential target for cancer therapy

J Plzák, J Bouček, V Bandúrová, M Kolář, M Hradilová… - Cancers, 2019 - mdpi.com
Similarly to other types of malignant tumours, the incidence of head and neck cancer is
increasing globally. It is frequently associated with smoking and alcohol abuse, and in a …

[HTML][HTML] Tumor microenvironment: an evil nexus promoting aggressive head and neck squamous cell carcinoma and avenue for targeted therapy

AA Bhat, P Yousuf, NA Wani, A Rizwan… - Signal transduction and …, 2021 - nature.com
Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease with a poor
prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have …

[HTML][HTML] Tumor microenvironment in head and neck squamous cell carcinoma

JM Curry, J Sprandio, D Cognetti, A Luginbuhl… - Seminars in …, 2014 - Elsevier
The tumor microenvironment (TME) of head and neck squamous cell carcinoma (HNSCC) is
comprised of cancer-associated fibroblasts (CAFs), immune cells, and other supporting …

[HTML][HTML] Tumor microenvironment and immune evasion in head and neck squamous cell carcinoma

A Elmusrati, J Wang, CY Wang - International journal of oral science, 2021 - nature.com
Head and neck squamous cell carcinoma (HNSCC), an aggressive malignancy, is
characterized by high morbidity and low survival rates with limited therapeutic options …

[HTML][HTML] Chemokine-cytokine networks in the head and neck tumor microenvironment

S Nisar, P Yousuf, T Masoodi, NA Wani… - International Journal of …, 2021 - mdpi.com
Head and neck squamous cell carcinomas (HNSCCs) are aggressive diseases with a
dismal patient prognosis. Despite significant advances in treatment modalities, the five-year …

[HTML][HTML] Targeting oral tumor microenvironment for effective therapy

HS Budi, B Farhood - Cancer Cell International, 2023 - Springer
Oral cancers are among the common head and neck malignancies. Different anticancer
therapy modalities such as chemotherapy, immunotherapy, radiation therapy, and also …

Portrait of a CAF: The story of cancer-associated fibroblasts in head and neck cancer

M Custódio, A Biddle, M Tavassoli - Oral Oncology, 2020 - Elsevier
Complex interactions take place during cancer formation and progression. In this regard,
there has been increasing focus on the non-malignant cells that make up the tumour …