[PDF] umn.edu

Re-aligning patient prognosis: the role of collagen in establishing an immunosuppressive microenvironment and facilitating cancer cell dissemination in pancreatic …

MK Callaway - 2021 - search.proquest.com
Pancreatic ductal adenocarcinoma (PDA) is an aggressive cancer with particularly poor
clinical outcomes, in part, because of a dramatically altered stromal environment and striking …
相关文章 所有 3 个版本
[PDF] archive.org

[PDF][PDF] Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma

HJ Rasmussen, DG Denardo, DK Wood… - scholar.archive.org
Pancreatic ductal adenocarcinoma (PDA) is an extremely metastatic and lethal disease.
Here in both murine and human PDA we demonstrate that extracellular matrix architecture …
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[HTML] nih.gov

[HTML][HTML] Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma

A Ray, MK Callaway, NJ Rodríguez-Merced… - JCI insight, 2022 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDA) is an extremely metastatic and lethal disease.
Here, in both murine and human PDA, we demonstrate that extracellular matrix architecture …
被引用次数：36 相关文章 所有 11 个版本
[HTML] annualreviews.org

[HTML][HTML] Tumor microenvironment in pancreatic cancer pathogenesis and therapeutic resistance

MH Sherman, GL Beatty - Annual Review of Pathology …, 2023 - annualreviews.org
Pancreatic ductal adenocarcinoma (PDAC) features a prominent stromal microenvironment
with remarkable cellular and spatial heterogeneity that meaningfully impacts disease …
被引用次数：115 相关文章 所有 4 个版本

The tumor microenvironment in pancreatic ductal adenocarcinoma: current perspectives and future directions

CJ Herting, I Karpovsky, GB Lesinski - Cancer and Metastasis Reviews, 2021 - Springer
Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal malignancies and is
characterized by a unique tumor microenvironment (TME) consisting of an abundant stromal …
被引用次数：44 相关文章 所有 6 个版本

Panoramic tumor microenvironment in pancreatic ductal adenocarcinoma

X Li, W Hou, C Xiao, H Yang, C Zhao, D Cao - Cellular Oncology, 2024 - Springer
Pancreatic ductal adenocarcinoma (PDAC) is notorious for its resistance to various
treatment modalities. The genetic heterogeneity of PDAC, coupled with the presence of a …
相关文章 所有 2 个版本
[HTML] mdpi.com

[HTML][HTML] Immune cell modulation of the extracellular matrix contributes to the pathogenesis of pancreatic cancer

RS Ahmad, TD Eubank, S Lukomski, BA Boone - Biomolecules, 2021 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with a five-year
survival rate of only 9%. PDAC is characterized by a dense, fibrotic stroma composed of …
被引用次数：27 相关文章 所有 10 个版本
[HTML] nih.gov

[HTML][HTML] Highly aligned stromal collagen is a negative prognostic factor following pancreatic ductal adenocarcinoma resection

CR Drifka, AG Loeffler, K Mathewson, A Keikhosravi… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Risk factors for pancreatic ductal adenocarcinoma (PDAC) progression after surgery are
unclear, and additional prognostic factors are needed to inform treatment regimens and …
被引用次数：223 相关文章 所有 9 个版本
[PDF] portlandpress.com

Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy

KJ Murphy, J Zhu, M Trpceski, BA Pereira… - Biochemical Society …, 2022 - portlandpress.com
The dense desmoplastic and fibrotic stroma is a characteristic feature of pancreatic ductal
adenocarcinoma (PDAC), regulating disease progression, metastasis and response to …
被引用次数：12 相关文章 所有 5 个版本
[PDF] sciencedirect.com

Compartment resolved proteomics reveals a dynamic matrisome in a biomechanically driven model of pancreatic ductal adenocarcinoma

AS Barrett, O Maller, MW Pickup, VM Weaver… - Journal of immunology …, 2018 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a severe fibrotic component
that compromises treatment, alters the immune cell profile and contributes to patient …
被引用次数：15 相关文章 所有 6 个版本