Current medical therapy and revascularization in peripheral artery disease of the lower limbs: impacts on subclinical chronic inflammation

AL Cecchini, F Biscetti, M Manzato, L Lo Sasso… - International Journal of …, 2023 - mdpi.com
Peripheral artery disease (PAD), coronary artery disease (CAD), and cerebrovascular
disease (CeVD) are characterized by atherosclerosis and inflammation as their underlying …

Novel strategies to promote resolution of inflammation to treat lower extremity artery disease

Q Zhang, F Li, RH Ritchie, OL Woodman, X Zhou… - Current Opinion in …, 2022 - Elsevier
Lower extremity artery disease (LEAD) is a chronic inflammatory disease that occurs when
atherosclerotic plaques form in the lower extremities, which may lead to amputation if not …

Pharmacotherapy and revascularization strategies of peripheral artery disease

E Moras, M Khan, DD Song, M Syed… - Current Problems in …, 2024 - Elsevier
The global epidemiological transition of atherosclerotic vascular diseases is witnessing a
rapid redistribution of its burden, shifting from high-income to low-and middle-income …

Integrating mechanisms in thrombotic peripheral arterial disease

M Nagy, PEJ van der Meijden, J Glunz, L Schurgers… - Pharmaceuticals, 2022 - mdpi.com
Peripheral arterial disease (PAD), a manifestation of systemic atherosclerosis, is
underdiagnosed in the general population. Despite the extensive research performed to …

Inflammatory biomarkers in peripheral artery disease: diagnosis, prognosis, and therapeutic challenges

Y Ozaki, T Imanishi, T Akasaka - Current Medicinal Chemistry, 2015 - ingentaconnect.com
Peripheral artery disease (PAD) is an inflammatory disease caused by atherosclerosis. It
has been demonstrated that PAD is related to chronic inflammation. While conventional risk …

Update on the pathophysiology and medical treatment of peripheral artery disease

J Golledge - Nature reviews cardiology, 2022 - nature.com
Approximately 6% of adults worldwide have atherosclerosis and thrombosis of the lower
limb arteries (peripheral artery disease (PAD)) and the prevalence is rising. PAD causes leg …

Inflammation in peripheral arterial disease (PAD)

S Santo Signorelli, M Anzaldi… - Current pharmaceutical …, 2012 - ingentaconnect.com
Peripheral arterial disease (PAD) affects a large number of individuals over the age of 55
years old, and data from studies has shown a relationship between inflammation, and PAD …

Management and Pharmacological Treatment of Peripheral Arterial Disease

SJ Leatham, KR Winckel… - Journal of Pharmacy …, 2024 - journals.sagepub.com
Background: Peripheral arterial disease (PAD) is a complex, heterogeneous condition that
has become a leading health concern globally. Peripheral arterial disease often co-exists …

[HTML][HTML] Peripheral Artery Disease: Underappreciated Impact and Residual Cardiovascular Risk Despite Revascularization

S Jansen, GJ de Borst, R Hinchliffe, M Teraa - Clinical Therapeutics, 2023 - Elsevier
This Commentary highlights the under-recognized prevalence and heavy burden of
peripheral artery disease (PAD) and its important role as a harbinger of complications of …

Preventive therapies in peripheral arterial disease

AJ Shah, N Pavlatos, DK Kalra - Biomedicines, 2023 - mdpi.com
Atherosclerosis, while initially deemed a bland proliferative process, is now recognized as a
multifactorial-lipoprotein-mediated inflammation-driven pathway. With the rising incidence of …