Perspectives of preimplantation genetic testing patients in Belgium on the ethics of polygenic embryo screening

M Siermann, JR Vermeesch, T Raivio, A Vanhie… - Reproductive …, 2024 - Elsevier
Research question What are the perspectives of preimplantation genetic testing patients in
Belgium on the ethics of preimplantation genetic testing for polygenic risk scoring (PGT-P) …

Preimplantation testing of embryos for polygenic related conditions: the ethical concerns surrounding it and the position of genetic counselors

ST Terek, A Gamma, M Zak, H Butts - Fertility and Sterility, 2021 - fertstert.org
Objective In recent years, commercial genetic testing companies have started testing,
manufacturing, and marketing technology aimed at providing embryos with polygenic risk …

“Are we not going too far?“: Socio-ethical considerations of preimplantation genetic testing using polygenic risk scores according to healthcare professionals

M Siermann, O Valcke, JR Vermeesch, T Raivio… - Social Science & …, 2024 - Elsevier
The recent introduction of polygenic risk scores within preimplantation genetic testing (PGT-
P) has been met with many concerns. To get more insights into the perspectives of relevant …

Limitations, concerns and potential: attitudes of healthcare professionals toward preimplantation genetic testing using polygenic risk scores

M Siermann, O Valcke, JR Vermeesch… - European Journal of …, 2023 - nature.com
Preimplantation genetic testing using polygenic risk scores (PGT-P) has recently been
introduced. However, PGT-P has been met with many ethical concerns. It is therefore …

Ready for polygenic risk scores? An analysis of regulation of preimplantation genetic testing in European countries

M Siermann, V van der Schoot, EM Bunnik… - Human …, 2024 - academic.oup.com
STUDY QUESTION Would the different regulatory approaches for preimplantation genetic
testing (PGT) in Europe permit the implementation of preimplantation genetic testing using …

A systematic review of the views of healthcare professionals on the scope of preimplantation genetic testing

M Siermann, Z Claesen, L Pasquier, T Raivio… - Journal of Community …, 2022 - Springer
Preimplantation genetic testing (PGT) involves testing embryos created through in vitro
fertilization for the presence of hereditary genetic disorders and chromosome abnormalities …

Contributing to the on-going debate around the clinical application of preimplantation embryo selection based on polygenic risk scores (PGT-P)

P Makrythanasis, G Kakourou, T Mamas… - European Journal of …, 2023 - nature.com
The article by Siermann et al.[1] in this issue presents the findings of a questionnaire-based
survey of 31 health care professionals (HCPs) involved in Preimplantation Genetic Testing …

[HTML][HTML] A review of normative documents on preimplantation genetic testing: Recommendations for PGT-P

M Siermann, O Tšuiko, JR Vermeesch, T Raivio… - Genetics in …, 2022 - Elsevier
Purpose Recently, preimplantation genetic testing (PGT) for polygenic conditions (PGT-P)
has been introduced commercially. In view of the lack of specific guidance on this …

Regulatory safeguards needed if preimplantation genetic testing for polygenic risk scores (PGT-P) is permitted in Singapore

AHB Chin, LW Lim, SM Muhsin - Journal of Medical Ethics, 2024 - jme.bmj.com
Singapore, a highly affluent island city-state located in Southeast Asia, has increasingly
leveraged new assisted reproductive technologies (ART) to overcome its dismal fertility rates …

A review on the motivations, decision-making factors, attitudes and experiences of couples using pre-implantation genetic testing for inherited conditions

T Hughes, T Bracewell-Milnes, S Saso… - Human …, 2021 - academic.oup.com
BACKGROUND In pre-implantation genetic testing (PGT), fertile couples undergo IVF with
genetic testing of embryos to avoid conceptions with a genetic condition. There is an …