The liver is the sixth most common site of primary cancer in humans, and generally arises in
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …

Liver metastases from gastrointestinal and non-gastrointestinal malignancies remain a
major cause of cancer-related mortality and a major clinical challenge. The liver has unique …

The initiation and progression of liver cancer, including hepatocellular carcinoma and
intrahepatic cholangiocarcinoma, are dependent on its tumor microenvironment. Immune …

Simple Summary Liver metastasis remains the major contributor in colorectal cancer-related
death. It has become clear that the unique immune features of liver microenvironment take …

Sustained hepatic inflammation, driven by alcohol consumption, nonalcoholic fatty liver
disease, and/or chronic viral hepatitis (hepatitis B and C), results in damage to parenchyma …

In contrast to most other malignancies, hepatocellular carcinoma (HCC), which accounts for
approximately 90% of primary liver cancers, arises almost exclusively in the setting of …

The liver is host to many metastatic cancers, particularly colorectal cancer, for which the last
2 decades have seen major advances in diagnosis and treatment. The liver is a vital organ …

The liver is the sixth most common site of primary cancer in humans and the fourth leading
cause of cancer‐related death in the world. Hepatocellular carcinoma (HCC) accounts for …

The liver is the largest organ in the human body and is prone for cancer metastasis.
Although the metastatic pattern can differ depending on the cancer type, the liver is the …

Liver metastasis, the leading cause of colorectal cancer mortality, exhibits a highly
heterogeneous and suppressive immune microenvironment. Here, we sequenced 97 …