Krüppel-like factor 5 (Klf5) is a zinc-finger transcription factor that controls various biological
processes, including cell proliferation and differentiation. We show that Klf5 is also an …

Krüppel-like factor 4 (KLF4) is an evolutionarily conserved zinc finger-containing
transcription factor that regulates diverse cellular processes such as cell proliferation …

Successful muscle regeneration following injury is essential for functional homeostasis of
skeletal muscles. Krüppel-like factor 15 (KLF15) is a metabolic transcriptional regulator in …

Background Krüppel-like factor 6 (KLF6) has been recently identified as a MEF2D target
gene involved in neuronal cell survival. In addition, KLF6 and TGFβ have been shown to …

In skeletal muscle differentiation, muscle-specific genes are regulated by two groups of
transcription factors, the MyoD and MEF2 families, which work together to drive the …

This study identifies KLF3 as a transcriptional regulator of muscle genes and reveals a novel
synergistic interaction between KLF3 and serum response factor (SRF). Using quantitative …

Skeletal muscle development is controlled by regulation of myoblast proliferation and
differentiation into muscle fibers. Growth factors such as fibroblast growth factors (FGFs) and …

Skeletal muscle atrophy is caused by various conditions, including aging, disuse related to a
sedentary lifestyle and lack of physical activity, and cachexia. Our insufficient understanding …

Maintenance of muscle structure and function depends on the precise organization of
contractile proteins into sarcomeres and coupling of the contractile apparatus to the …

Krüppel-like factor 4 (Klf4) is a transcription factor involved in differentiation and proliferation
in multiple tissues. We demonstrated previously that tamoxifen-induced deletion of the Klf4 …