[PDF][PDF] B Cell Deficiency and Implications in HIV Pathogenesis: Unraveling the Complex Interplay

EI Obeagu, O AmaezeAA, GU Obeagu - Elite Journal of Nursing and …, 2024 - academia.edu
This review delves into the intricate relationship between B cell deficiency and its profound
implications in the pathogenesis of human immunodeficiency virus (HIV) infection. As a key …

[PDF][PDF] Understanding B Lymphocyte Functions in HIV Infection: Implications for Immune Dysfunction and Therapeutic Strategies

EI Obeagu, GU Obeagu - Elite Journal of Medicine, 2024 - researchgate.net
Abstract Human Immunodeficiency Virus (HIV) infection poses a significant challenge to the
immune system, with B lymphocytes playing a central role in orchestrating humoral immune …

[PDF][PDF] Implications of B Lymphocyte Dysfunction in HIV/AIDS

EI Obeagu, GU Obeagu - Elite Journal of Immunology, 2024 - researchgate.net
The ongoing battle against Human Immunodeficiency Virus (HIV) necessitates a
comprehensive understanding of the intricate interplay between various components of the …

[PDF][PDF] Unveiling B Cell Mediated Immunity in HIV Infection: Insights, Challenges, and Potential Therapeutic Avenues

EI Obeagu, AF Anyiam, GU Obeagu - Elite Journal of HIV, 2024 - researchgate.net
Abstract Human Immunodeficiency Virus (HIV) poses a significant global health challenge,
necessitating a deeper comprehension of the immune responses engaged in infection. B …

B cells in HIV infection and disease

S Moir, AS Fauci - Nature Reviews Immunology, 2009 - nature.com
In recent years, intense research efforts have been dedicated to elucidating the pathogenic
mechanisms of HIV-associated disease progression. In addition to the progressive depletion …

B lymphocyte dysfunctions in HIV infection

A De Milito - Current HIV research, 2004 - ingentaconnect.com
HIV establishes a chronic and latent infection that is not eliminated by the host immune
defences. The virus induces extensive damage to the immune system, through virus-related …

Impairment of B-cell functions during HIV-1 infection

S Amu, N Ruffin, B Rethi, F Chiodi - Aids, 2013 - journals.lww.com
A variety of B-cell dysfunctions are manifested during HIV-1 infection, as reported early
during the HIV-1 epidemic. It is not unusual that the pathogenic mechanisms presented to …

Insights into B cells and HIV‐specific B‐cell responses in HIV‐infected individuals

S Moir, AS Fauci - Immunological reviews, 2013 - Wiley Online Library
Human immunodeficiency virus (HIV) disease is associated with dysregulation and
dysfunction involving all major lymphocyte populations, including B cells. Such perturbations …

Pathogenic mechanisms of B-lymphocyte dysfunction in HIV disease

S Moir, AS Fauci - Journal of Allergy and Clinical Immunology, 2008 - Elsevier
HIV disease is associated with abnormalities in all major lymphocyte populations, including
B cells. Aberrancies in the B-cell compartment can be divided into 3 broad categories …

[PDF][PDF] Harnessing B cell responses for personalized approaches in HIV Management

EI Obeagu, GU Obeagu - Elite Journal of Immunology, 2024 - researchgate.net
This comprehensive review explores the forefront of HIV management through the lens of
personalized medicine, with a specific focus on harnessing B cell responses. The dynamic …