Chronic inflammation in response to lipoprotein accumulation in the arterial wall is central in
the development of atherosclerosis. Both innate and adaptive immunity are involved in this …

Chronic inflammation drives the development of atherosclerosis, and adaptive immunity is
deeply involved in this process. Initial studies attributed a pathogenic role to T cells in …

Atherosclerosis is a chronic process associated with arterial inflammation, the accumulation
of lipids, plaque formation in vessel walls, and thrombosis with late mortal complications …

Far from being merely a passive cholesterol accumulation within the arterial wall, the
development of atherosclerosis is currently known to imply both inflammation and immune …

Adaptive immune response plays an important role in atherogenesis. In atherosclerosis, the
proinflammatory immune response driven by Th1 is predominant but the anti-inflammatory …

Atherosclerosis involves the formation of inflammatory arterial lesions and is one of the most
common causes of death globally. It has been evident for more than 20 years that adaptive …

Although the pathogenic role of T cells in atherogenesis is well established, the function of
the various T-cell subsets is far from clear. Whereas activation of the T-helper type 1 (Th1) …

Atherosclerosis is a chronic inflammatory disease that is initiated by the retention and
accumulation of cholesterol-containing lipoproteins, particularly low-density lipoprotein, in …

Atherosclerosis is an inflammatory and multifaceted disorder resulting from the accumulation
of lipid droplets and several types of immune cells, including macrophages, T and B …

Atherosclerosis is an inflammatory disease of the arterial wall where both innate and
adaptive T-cell-driven immunoinflammatory responses contribute to disease development …