[HTML][HTML] The fibroblast growth factor receptors in breast cancer: from oncogenesis to better treatments

N Sobhani, C Fan, P O. Flores-Villanueva… - International journal of …, 2020 - mdpi.com
Breast cancer (BC) is the most frequent form of malignancy and second only to lung cancer
as cause of deaths in women. Notwithstanding many progresses made in the field …

Potential for targeting the fibroblast growth factor receptors in breast cancer

NE Hynes, JH Dey - Cancer research, 2010 - AACR
Breast cancer is the most common cancer of women, accounting yearly for approximately
30% of newly diagnosed cases and ranking second as a cause of death. Despite …

Fibroblast growth factor receptors in breast cancer

S Wang, Z Ding - Tumor Biology, 2017 - journals.sagepub.com
Fibroblast growth factor receptors are growth factor receptor tyrosine kinases, exerting their
roles in embryogenesis, tissue homeostasis, and development of breast cancer. Recent …

[HTML][HTML] The FGF/FGFR system in breast cancer: oncogenic features and therapeutic perspectives

MF Santolla, M Maggiolini - Cancers, 2020 - mdpi.com
Simple Summary The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR)
system represents an emerging therapeutic target in breast cancer. Here, we discussed …

Targeting FGFR pathway in breast cancer

J Perez-Garcia, E Muñoz-Couselo, J Soberino… - The Breast, 2018 - Elsevier
Developments in breast cancer biology over the last years have permitted deconstructing
the molecular profile of the most relevant breast cancer subtypes. This has led to an …

Fibroblast growth factor receptor signalling dysregulation and targeting in breast cancer

C Francavilla, CS O'Brien - Open Biology, 2022 - royalsocietypublishing.org
Fibroblast Growth Factor Receptor (FGFR) signalling plays a critical role in breast embryonal
development, tissue homeostasis, tumorigenesis and metastasis. FGFR, its numerous FGF …

[HTML][HTML] Fibroblast growth factor receptors in breast cancer: expression, downstream effects, and possible drug targets

M Tenhagen, PJ Van Diest, IA Ivanova… - Endocrine-related …, 2012 - erc.bioscientifica.com
Cancer treatments are increasingly focusing on the molecular mechanisms underlying the
oncogenic processes present in tumors of individual patients. Fibroblast growth factor …

[HTML][HTML] Challenges and opportunities in the targeting of fibroblast growth factor receptors in breast cancer

VK Jain, NC Turner - Breast Cancer Research, 2012 - Springer
Activation of the fibroblast growth factor receptor pathway is a common event in many cancer
types. Here we review the role of fibroblast growth factor receptor signalling in breast cancer …

[HTML][HTML] Current status of fibroblast growth factor receptor-targeted therapies in breast cancer

N Sobhani, A Ianza, A D'angelo, G Roviello, F Giudici… - Cells, 2018 - mdpi.com
Breast cancer (BC) is the most common malignancy and second only to lung cancer in terms
of mortality in women. Despite the incredible progress made in this field, metastatic breast …

The FGF/FGF receptor axis as a therapeutic target in breast cancer

NJ Brady, P Chuntova, LK Bade… - Expert review of …, 2013 - Taylor & Francis
FGF receptor (FGFR) signaling is a vital component of both embryonic and postnatal
mammary gland development, which has prompted researchers to investigate both its …