The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine

G Cutshaw, S Uthaman, N Hassan… - Chemical …, 2023 - ACS Publications
Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …

Advances in Raman spectroscopy and imaging for biomedical research

S Siddhanta, AN Kuzmin, A Pliss, AS Baev… - Advances in Optics …, 2023 - opg.optica.org
Starting with a historical account of evolution in Raman spectroscopy, in this review we
provide details of the advancements that have pushed detection limits to single molecules …

Raman spectroscopy: an emerging tool in neurodegenerative disease research and diagnosis

G Devitt, K Howard, A Mudher… - ACS chemical …, 2018 - ACS Publications
The pathogenesis underlining many neurodegenerative diseases remains incompletely
understood. The lack of effective biomarkers and disease preventative medicine demands …

The role of Raman spectroscopy within quantitative metabolomics

C Lima, H Muhamadali… - Annual Review of …, 2021 - annualreviews.org
Ninety-four years have passed since the discovery of the Raman effect, and there are
currently more than 25 different types of Raman-based techniques. The past two decades …

Prospects of surface-enhanced Raman spectroscopy for biomarker monitoring toward precision medicine

J Plou, PS Valera, I Garcia, CDL de Albuquerque… - ACS …, 2022 - ACS Publications
Future precision medicine will be undoubtedly sustained by the detection of validated
biomarkers that enable a precise classification of patients based on their predicted disease …

[HTML][HTML] Raman spectroscopy for medical diagnostics—From in-vitro biofluid assays to in-vivo cancer detection

K Kong, C Kendall, N Stone, I Notingher - Advanced drug delivery reviews, 2015 - Elsevier
Raman spectroscopy is an optical technique based on inelastic scattering of light by
vibrating molecules and can provide chemical fingerprints of cells, tissues or biofluids. The …

Raman spectroscopy on brain disorders: transition from fundamental research to clinical applications

JC Ranasinghe, Z Wang, S Huang - Biosensors, 2022 - mdpi.com
Brain disorders such as brain tumors and neurodegenerative diseases (NDs) are
accompanied by chemical alterations in the tissues. Early diagnosis of these diseases will …

Towards development of a novel universal medical diagnostic method: Raman spectroscopy and machine learning

NM Ralbovsky, IK Lednev - Chemical Society Reviews, 2020 - pubs.rsc.org
Many problems exist within the myriad of currently employed screening and diagnostic
methods. Further, an incredibly wide variety of procedures are used to identify an even …

Spectral analysis of multiplex Raman probe signatures

BR Lutz, CE Dentinger, LN Nguyen, L Sun, J Zhang… - ACS …, 2008 - ACS Publications
Raman nanoparticle probes are an emerging new class of optical labels for interrogation of
physiological and pathological processes in bioassays, cells, and tissues. Although their …

Unveiling cancer metabolism through spontaneous and coherent Raman spectroscopy and stable isotope probing

J Xu, T Yu, CE Zois, JX Cheng, Y Tang, AL Harris… - Cancers, 2021 - mdpi.com
Simple Summary Raman spectroscopy and imaging are label-free, non-destructive
techniques to study cellular metabolism with subcellular spatial resolution. This review …