Deciphering microbiota functions is crucial to predict ecosystem sustainability in response to
global change. High-throughput sequencing at the individual or community level has …

Shotgun metagenomics and marker gene amplicon sequencing can be used to directly
measure or predict the functional repertoire of the microbiota en masse, but current methods …

Background: The objectives of any metagenomic study typically include identification of
resident microbes and their relative proportions (taxonomic analysis), profiling functional …

Background Taxonomic profiling of ribosomal RNA (rRNA) sequences has been the
accepted norm for inferring the composition of complex microbial ecosystems. Quantitative …

Communities of microorganisms (microbiota) are present in all habitats on Earth and are
relevant for agriculture, health, and climate. Deciphering the mechanisms that determine …

Abstract Background Sequencing of 16S rRNA genes has become a powerful technique to
study microbial communities and their responses towards changing environmental …

Background Advances in microbiome science are being driven in large part due to our
ability to study and infer microbial ecology from genomes reconstructed from mixed …

Background What is a healthy microbiome? The pursuit of this and many related questions,
especially in light of the recently recognized microbial component in a wide range of …

The data output from microbiome research is growing at an accelerating rate, yet mining the
data quickly and efficiently remains difficult. There is still a lack of an effective data structure …

Genomics is fast becoming a routine tool in medical diagnostics and cutting-edge
biotechnologies. Yet, its use for environmental biomonitoring is still considered a futuristic …