The mammary gland of the lactating mouse synthesizes and secretes milk lipid equivalent to
its entire body weight in a single 20-day lactation cycle, making it one of the most active lipid …

Lipids, primarily triglycerides, are major milk constituents of most mammals, providing a
large percentage of calories, essential fatty acids and bioactive lipids required for neonatal …

Background The molecular events associated with regulation of milk fat synthesis in the
bovine mammary gland remain largely unknown. Our objective was to study mammary …

Expression of genes for lipid biosynthetic enzymes during initiation of lactation in humans is
unknown. Our goal was to study mRNA expression of lipid metabolic enzymes in human …

The molecular physiology underlying human milk production is largely unknown because of
limitations in obtaining tissue samples. Determining gene expression in normal lactating …

The lipid component of milk provides the critical nutritional source for generating both
energy and essential nutrients to the growth of the newborn. Three types of substrate are …

The lactating mammary gland synthesizes large amounts of triglyceride from fatty acids
derived from the blood and from de novo lipogenesis. The latter is significantly increased at …

The mammary gland undergoes dramatic functional and metabolic changes during the
transition from late pregnancy to lactation. To better understand the molecular events …

The mammary gland has an incredible level of organization and a remarkable ability to
convert circulating nutrients into milk components. This review highlights four areas of high …

Background Studies of normal human mammary gland development and function have
mostly relied on cell culture, limited surgical specimens, and rodent models. Although RNA …