Cancer prevention and control requires consideration of complex interactions between
multilevel factors. System dynamics modeling, which consists of diagramming and …

Systems epidemiology offers a more comprehensive and holistic approach to studies of
cancer in populations by considering high dimensionality measures from multiple domains …

Background: Although cancer research has advanced at a rapid pace, a gap remains
between what is known about how to improve cancer prevention and control (CPC) and …

ABSTRACT Introduction Precision Medicine (PM), especially in oncology, involve diagnostic
and complex treatment pathways that are based on genomic features. To conduct evaluation …

Cancer systems epidemiology: Overcoming misconceptions and integrating systems
approaches into cancer research | PLOS Medicine Skip to main content Advertisement …

Background Much of the cancer burden in the USA is preventable, through application of
existing knowledge. State-level funders and public health practitioners are in ideal positions …

Drawing on concepts from experimental biology, computer science, informatics,
mathematics, and statistics, systems biologists integrate data across diverse platforms and …

Abstract The National Cancer Institute (NCI) Cancer Moonshot initiative seeks to accelerate
cancer research for the USA. One of the scientific priorities identified by the Moonshot's Blue …

Accurate and reliable model representations of cancer dynamics are milestones in the field
of cancer research. Mathematical modeling approaches are abundantly used in cancer …

Current cancer therapies target a limited set of tumor features, rather than considering the
tumor as a whole. Systems biology aims to reveal therapeutic targets associated with a …