Background Clinical trials remain the cornerstone of evidence-based health care. As of July
1, 2021, there were 382,313 clinical trials registered on ClinicalTrials. gov, an average of …

There is a well-documented gap between research and practice in many areas of behavioral
medicine. This gap is due in part to limitations in the capacity of the research database to …

Background Non-communicable chronic diseases are linked to behavioral risk factors
(including smoking, poor diet and physical inactivity), so effective behavior change …

Innovative, groundbreaking science relies upon preliminary studies (aka pilot, feasibility,
proof-of-concept). In the behavioral sciences, almost every large-scale intervention is …

This editorial discusses the implications of two important trendsinhealthresearchforenhancingthedesi…
, evaluation, and reporting of applied research and evaluation studies. The first trendisthegapbetweenresearchfindingsand …

The article comments on the developments in researches about behavioral medicine in the
US Current behavioral trial evidence reflects a pronounced emphasis on traditional …

Understanding the varied applicability of evidence across popula-tions and settings, and its
uses and limitations to help professionals and communities advance the goals of health …

Purpose-guided trial design (PGTD) is a novel heuristic framework for planning randomized
controlled trials of health-related behavioral interventions. Its use helps to ensure that the …

Clinical and health services researchers seek to discover effective programs, practices, and
interventions to improve people's health. The current paradigm for evidence generation is …

Background: Randomized clinical trials provide gold-standard evidence for the efficacy of
interventions, but have limitations, including highly selected populations that make inference …