[HTML][HTML] Human islet isolation and distribution efforts for clinical and basic research

N Ng, WX Tan, Y Koh, A Teo - OBM Transplantation, 2019 - lidsen.com
The ability to routinely and reproducibly obtain purified human islets has facilitated
substantial progress in providing a safe and reliable treatment option for adult patients of …

focused isolation of human islets from donors with and without diabetes at the Alberta Diabetes Institute IsletCore

J Lyon, JE Manning Fox, AF Spigelman, R Kim… - …, 2016 - academic.oup.com
Recent years have seen an increased focus on human islet biology, and exciting findings in
the stem cell and genomic arenas highlight the need to define the key features of mature …

[HTML][HTML] Use of human islets to understand islet biology and diabetes: progress, challenges and suggestions

NJ Hart, AC Powers - Diabetologia, 2019 - Springer
Over the last two decades, improved access to human islets and the development of human
islet distribution networks have enabled the use of millions of human islets in hundreds of …

Human pancreatic islets and diabetes research

JS Kaddis, BJ Olack, J Sowinski, J Cravens… - Jama, 2009 - jamanetwork.com
Human islet research is crucial to understanding the cellular biology of the pancreas in
developing therapeutic options for diabetes patients and in attempting to prevent the …

Islets for research: nothing is perfect, but we can do better.

R Nano, JA Kerr-Conte, D Bosco, M Karlsson… - Diabetes, 2019 - europepmc.org
In December 2018, Diabetes and Diabetologia began requiring authors of papers reporting
data obtained from studies on human islets to report critical characteristics of the human …

[HTML][HTML] A call for improved reporting of human islet characteristics in research articles

V Poitout, LS Satin, SE Kahn, DA Stoffers, P Marchetti… - Diabetologia, 2019 - Springer
the extent possible, standardisation of the preparations and methods used by individual
laboratories. Such objectives are aligned with the current emphasis placed on scientific …

Isolating the elusive islet

DW Scharp, R Downing, RC Merrell, M Greider - Diabetes, 1980 - Am Diabetes Assoc
The lack of a technique that allows mass isolation of intact, viable human islets is part of the
reason that islet transplantation has not become available to the human diabetic. This report …

Clinical islet isolation

WJ Hawthorne, L Williams, YV Chew - … Islet Isolation: From the Mouse to …, 2016 - Springer
The overarching success of islet transplantation relies on the success in the laboratory to
isolate the islets. This chapter focuses on the processes of human islet cell isolation and the …

[HTML][HTML] The integrated islet distribution program answers the call for improved human islet phenotyping and reporting of human islet characteristics in research …

M Brissova, JC Niland, J Cravens, B Olack, J Sowinski… - Diabetologia, 2019 - Springer
To the Editor: In recent years, the need for enhanced rigour, reproducibility and transparency
in biomedical research has been the topic of much discussion. The National Institutes of …

Optimal Time to Ship Human Islets Post Tissue Culture to Maximize Islet Recovery

BJ Olack, M Alexander, CJ Swanson… - Cell …, 2020 - journals.sagepub.com
Access to functional high-quality pancreatic human islets is critical to advance diabetes
research. The Integrated Islet Distribution Program (IIDP), a major source for human islet …