Transendothelial leukocyte migration is an early event in the progression of vascular
inflammation, the underlying molecular mechanism of atherosclerosis. Inflammatory …

Leukocyte infiltration in atherosclerosis has been extensively investigated by using
histological techniques on fixed tissues. In this study, intravital microscopic observations of …

Evaluation of: Llodrá J, Angeli V, Liu J, Trogan E, Fisher AE, Randolph GJ: Emigration of
monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not …

Atherosclerosis is currently the leading factor of death in developed countries. It is now
recognized as a chronic immune-inflammatory disease, whose initial stages involve the …

The accumulation of leukocytes in atherosclerotic lesions is of fundamental importance in
the development of atherosclerosis. Consequently, the adhesive and signaling mechanisms …

Leukocyte trafficking is a key pathological process during the formation of atheroma. As the
acute complications associated with atherosclerosis (heart attack and stroke) are the major …

Afew years ago, I was asked to give a series of lectures to our second-year medical students
on basic inflammatory mechanisms. I was taking the place of the late Russell Ross, who had …

Atherosclerosis is a chronic inflammatory disease of the arterial wall and an increasing body
of evidence suggests that the immune system actively participates in the initiation …

Background—Monocytes play a key role in atherogenesis, but their participation has been
discerned largely via ex vivo analyses of atherosclerotic lesions. We sought to establish a …

One of the earliest cellular events recognized so far in the development of the
atherosclerotic lesion is the adherence of monocytes to the endothelium. Adherent …