Novel avenues for identification of new antifungal drugs and current challenges
J Jampilek - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Some of the fungi have become pathogenic to humans, and these opportunistic
pathogens are able to cause severe systemic mycoses. Areas covered The number of …
pathogens are able to cause severe systemic mycoses. Areas covered The number of …
[HTML][HTML] Sources of antifungal drugs
G Vanreppelen, J Wuyts, P Van Dijck, P Vandecruys - Journal of Fungi, 2023 - mdpi.com
Due to their eukaryotic heritage, the differences between a fungal pathogen's molecular
makeup and its human host are small. Therefore, the discovery and subsequent …
makeup and its human host are small. Therefore, the discovery and subsequent …
Potential targets for the development of new antifungal drugs
H Su, L Han, X Huang - The journal of antibiotics, 2018 - nature.com
In recent years, incidences of invasive fungal infections have greatly increased, especially in
immunosuppressed patients, but most today's antifungal drugs are not completely effective …
immunosuppressed patients, but most today's antifungal drugs are not completely effective …
Recent progress on antifungal drug development
Invasive fungal infections are a serious threat to public health, particularly to people with
compromised or suppressed immunity. Although the current antifungal therapies have been …
compromised or suppressed immunity. Although the current antifungal therapies have been …
[HTML][HTML] New horizons in antifungal therapy
KM Pianalto, JA Alspaugh - Journal of Fungi, 2016 - mdpi.com
Recent investigations have yielded both profound insights into the mechanisms required by
pathogenic fungi for virulence within the human host, as well as novel potential targets for …
pathogenic fungi for virulence within the human host, as well as novel potential targets for …
Emerging novel antifungal agents
JM Fostel, PA Lartey - Drug discovery today, 2000 - Elsevier
Promising new compounds have recently been identified in an effort to supplement the
relatively sparse portfolio of antifungal drugs. Many of these compounds have defined …
relatively sparse portfolio of antifungal drugs. Many of these compounds have defined …
Antifungal drugs: New insights in research & development
The need for better antifungal therapy is commonly accepted in view of the high mortality
rates associated with systemic infections, the low number of available antifungal classes …
rates associated with systemic infections, the low number of available antifungal classes …
Progress in antifungal drug discovery
MB Anderson, T Roemer, R Fabrey - 2003 - Elsevier
Undoubtedly, innovative research efforts will continue in the 21 st century as we seek to
minimize the incidence of opportunistic fungal infections worldwide, exploit available and …
minimize the incidence of opportunistic fungal infections worldwide, exploit available and …
Novel antifungal agents: a patent review (2013-present)
M Victoria Castelli, M Gabriel Derita… - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: Superficial infections involving the skin and mucosa are the most common
fungal disease in humans. Fungi can also produce invasive infections (IFI), which are …
fungal disease in humans. Fungi can also produce invasive infections (IFI), which are …
Editorial [Hot Topic: Fungal Infections and Antifungal Strategies (Guest Editor: Karin Thevissen)]
K Thevissen - Current Drug Targets, 2005 - ingentaconnect.com
The current review issue regarding'Fungal Infections and Antifungal Strategies' unites
reviews regarding (i) the infection process of pathogenic fungi resulting in topical or systemic …
reviews regarding (i) the infection process of pathogenic fungi resulting in topical or systemic …