Both type 1 and type 2 diabetes mellitus occur throughout the animal kingdom, and diabetic
kidney disease has often been documented. We have tried to assemble some of the recent …

Diabetic nephropathy is currently the single major cause of kidney failure in the
industrialized world. Animal models have been used in the attempt to develop innovative …

Diabetic nephropathy is the leading cause of end stage renal diseases worldwide. Even
though several diabetic animal models exist, not a single one develops renal changes …

Diabetic nephropathy in the human is one of the major secondary complications of diabetes.
Diabetic nephropathy is the clinical term used to describe diabetic renal disease when it has …

Diabetic nephropathy (DN) affects at least 30% of insulin dependent diabetic patients
(Andersen et al., 1983) and a lesser percentage of NIDDM subjects (Mogensen, 1984). This …

Diabetes mellitus affects the kidney in stages. At the onset of diabetes mellitus, in a subset of
diabetic patients the kidneys grow large, and glomerular filtration rate (GFR) becomes …

Diabetic nephropathy is the most common cause of end-stage renal disease. Therefore,
novel therapies for the suppression of diabetic nephropathy must be developed. Rodent …

Kidney disease, characterized by proteinuria and glomerular lesions, is a common
complication of spontaneous diabetes mellitus in many animal species. It occurs in animals …

Nephropathy in patients with type I and II diabetes mellitus is a rapidly increasing problem
worldwide. Studies using both glomerular and tubular cells have delineated some of the …

One-third of diabetes mellitus patients develop diabetic nephropathy, and with underlying
mechanisms unknown it is imperative that diabetic animal models resemble human disease …