Background Researches indicate that epigenetics was involved in osteoarthritis (OA). The
purpose of this study was to describe the alterations of DNA methylation in hip and knee OA …

Objectives Transcriptional changes in cartilage can impact function by causing degradation
such as that which occurs during the development of osteoarthritis (OA). Epigenetic …

Background Evidence suggests that epigenetics plays a role in osteoarthrits (OA). The aim
of the study was to describethe genome wide DNA methylation changes in hip and knee OA …

Objective To perform a genome‐wide DNA methylation study to identify DNA methylation
changes in osteoarthritic (OA) cartilage tissue. Methods The contribution of differentially …

Objective Alterations in DNA methylation patterns have been found to correlate with several
diseases including osteoarthritis (OA). The aim of this study was to identify, for the first time …

Objective To perform a genome‐wide DNA methylation study to identify differential DNA
methylation patterns in subchondral bone underlying eroded and intact cartilage from …

Genome-wide expression and methylation profiling reveal candidate genes in osteoarthritis
Page 1 Clinical and Experimental Rheumatology 2017 Clinical and Experimental …

Aim Osteoarthritis (OA) is caused by complex interactions between genetic and
environmental factors. Epigenetic mechanisms control the expression of genes and are …

Genetics and epigenetics are important subjects in the field of osteoarthritis (OA) research.
DNA methylation may affect gene transcription, but the specific mechanisms have remained …

Objective The aim of this study was to characterize the genome‐wide DNA methylation
profile of chondrocytes from knee and hip cartilage obtained from patients with osteoarthritis …