A series of furan-based hydrazones: design, synthesis, and evaluation of antimicrobial activity, cytotoxicity and genotoxicity

MD Altintop, B Sever, ÖA Eklioğlu… - Letters in Drug …, 2020 - ingentaconnect.com
Background: Hydrazones, frequently occurring motifs in many bioactive molecules, have
attracted a great deal of interest as potent antimicrobial agents. Objective: The aim of this …

Hydrazone analogues with promising antibacterial profiles: Synthesis, morphology, in vitro and in silico approaches

M Nabizadeh, MR Naimi‐Jamal… - Letters in Applied …, 2022 - academic.oup.com
The emergence of resistance to antibacterial drugs remains an important global threat that
necessitates an urgent need for the discovery of alternative drugs. This study was …

[PDF][PDF] Therapeutic review exploring antimicrobial potential of hydrazones as promising lead

G Uppal, S Bala, S Kamboj, M Saini - Der Pharma Chemica, 2011 - researchgate.net
This review includes detailed study of structures of various hydrazones synthesized and
evaluated for their antimicrobial activity. Hydrazone is a class of organic compounds with …

Synthesis of Novel Hydrazone Derivatives of 2, 5-difluorobenzoic Acid as Potential Antibacterial Agents

R Narisetty, KB Chandrasekhar… - Letters in Drug …, 2013 - ingentaconnect.com
Hydrazones are important classes of compounds found in many synthetic products. Due to
their importance in synthetic chemistry, the present article reports the synthesis of twelve …

Synthesis, anticancer and antimicrobial evaluation of new pyridyl and thiazolyl clubbed hydrazone scaffolds

MB Muluk, AS Ubale, ST Dhumal… - Synthetic …, 2020 - Taylor & Francis
A series of new hydrazones bearing pyridyl and thiazolyl scaffolds have been synthesized
and evaluated for their in vitro anticancer and antimicrobial activities. The anticancer activity …

[HTML][HTML] Synthesis, in vitro and in silico studies of some novel 5-nitrofuran-2-yl hydrazones as antimicrobial and antitubercular agents

HAK Abdel-Aziz, WM Eldehna, M Fares… - Biological and …, 2015 - jstage.jst.go.jp
In this study, we synthesized two series of novel 5-nitrofuran-2-carbohydrazides 21a–h and
22a–e in addition to a third series of thiophene-2-carbohydrazides 23a–g to develop potent …

A systematic review on synthetic and antimicrobial bioactivity of the multifaceted hydrazide derivatives

A Ansari, S Tauro, S Asirvatham - Mini-Reviews in Organic …, 2022 - ingentaconnect.com
To overcome the upsurge of antimicrobial resistance that has emerged in recent years, there
is a need for the development of newer hits having satisfying anti-infective activity …

Updated information on antimicrobial activity of hydrazide–hydrazones

Ł Popiołek - International Journal of Molecular Sciences, 2021 - mdpi.com
Hydrazide–hydrazones possess a wide spectrum of bioactivity, including antibacterial,
antitubercular, antifungal, anticancer, anti-inflammatory, anticonvulsant, antidepressant …

Synthesis, in silico study and in vitro anti-microbial evaluation of some new N-benzoyl-N'-[2-(4-chloro-phenoxy)-acetyl]-hydrazides analogs

FH Al-Ostoot, YHE Mohammed… - Journal of Applied …, 2019 - japsonline.com
In bacterial resistance duty, the prompt increase against existent anti-microbial drugs is a
challenging universal health problem. Bacteria represent a highly significant threat globally …

[PDF][PDF] Antimicrobial potential of hydrazone scaffold

V Kumar - Int J Acad Res Dev, 2018 - researchgate.net
Discovery of new chemical entities as efficient and non-toxic chemotherapeutic agents is the
only way to overcome the challenging problems of infectious microbial diseases which exist …