Mucoadhesive chitosan-coated PLGA nanoparticles for oral delivery of ferulic acid

IA Lima, NM Khalil, TT Tominaga… - Artificial cells …, 2018 - Taylor & Francis
This paper describes the development and in vitro evaluation of poly (lactic-co-glycolic
acid)(PLGA) nanoparticles coated with chitosan (CS) for oral delivery of ferulic acid (FA) …

Zein-casein-lysine multicomposite nanoparticles are effective in modulate the intestinal permeability of ferulic acid

G Heep, A Almeida, R Marcano, D Vieira… - International journal of …, 2019 - Elsevier
The objective of this study was to develop zein-casein-lysine nanoparticles to modulate the
intestinal permeability of ferulic acid (FA), a bioactive compound with proven antioxidant …

Use of combined nanocarrier system based on chitosan nanoparticles and phospholipids complex for improved delivery of ferulic acid

DR Telange, SP Jain, AM Pethe, PS Kharkar… - International journal of …, 2021 - Elsevier
A novel nanocarrier system of phospholipids complex loaded chitosan nanoparticles
(FAPLC CNPs) was developed to improve the oral bioavailability and antioxidant potential of …

Studies on lactoferrin nanoparticles of gambogic acid for oral delivery

ZH Zhang, XP Wang, WY Ayman, WLL Munyendo… - Drug …, 2013 - Taylor & Francis
Abstract Purpose: Lactoferrin (Lf), a mammalian cationic iron-binding glycoprotein belonging
to the transferrin (Tf) family, has been widely used in a variety of fields ranging from treating …

Wheat germ agglutinin-conjugated chitosan–Ca–alginate microparticles for local colon delivery of 5-FU: Development and in vitro characterization

MG Dodov, S Calis, MS Crcarevska… - International journal of …, 2009 - Elsevier
The aim of this work was to prepare lectin-conjugated chitosan–Ca–alginate microparticles
(MPs) loaded with acid-resistant particles of 5-fluorouracil (5-FU) for efficient local treatment …

[HTML][HTML] 5-fluorouracil-loaded folic-acid-fabricated chitosan nanoparticles for site-targeted drug delivery cargo

S Ullah, AK Azad, A Nawaz, KU Shah, M Iqbal… - Polymers, 2022 - mdpi.com
Nanoparticles play a vital role in cancer treatment to deliver or direct the drug to the
malignant cell, avoiding the attacking of normal cells. The aim of the study is to formulate …

Novel alginate-enclosed chitosan–calcium phosphate-loaded iron-saturated bovine lactoferrin nanocarriers for oral delivery in colon cancer therapy

JR Kanwar, G Mahidhara, RK Kanwar - Nanomedicine, 2012 - Taylor & Francis
Aim: To develop polymeric-ceramic nanocarriers (NCs) in order to achieve oral delivery of
the anticancer neutraceutical iron-saturated bovine lactoferrin (Fe-bLf) protein. Materials & …

Development and in vitro evaluation of surface modified poly (lactide-co-glycolide) nanoparticles with chitosan-4-thiobutylamidine

V Grabovac, A Bernkop-Schnürch - Drug development and …, 2007 - Taylor & Francis
The objective of this study was to develop a nanoparticulate drug delivery system based on
the surface modification of poly (lactide-co-glycolide)(PLGA) nanoparticles with a thiolated …

Cellular uptake and transport characteristics of chitosan modified nanoparticles in Caco-2 cell monolayers

T Dou, J Wang, C Han, X Shao, J Zhang… - International journal of …, 2019 - Elsevier
The bioadhesive drug delivery systems, chitosan modified nanoparticles, can efficiently
adhere to mucosal surface of gastrointestinal tract and prolong residence time but a deeper …

Ferulic acid loaded poly-d, l-lactide-co-glycolide nanoparticles: systematic study of particle size, drug encapsulation efficiency and anticancer effect in non-small cell …

JPJ Merlin, NR Prasad, SMA Shibli - Biomedicine & Preventive Nutrition, 2012 - Elsevier
Ferulic acid (FA) is a phenolic phytonutrient, which possesses strong anticancer effect.
However, its prominent application in cancer is limited due to poor bioavailability at the …