Apical periodontitis is a common clinical disease caused by bacteria; bacterial metabolites
can cause an imbalance in bone homeostasis, bone mass reduction, and tooth loss. Bone …

Expression characteristics of bone morphogenetic protein-3 (BMP-3) in the process of
orthodontic tooth movement was investigated. Forty-eight rats were randomly divided into …

Orthodontic tooth movement (OTM) is initiated by mechanical force and featured as alveolar
bone remodeling. Periodontal ligament cells (PDLCs) are one of the major cell components …

Periodontal ligament (PDL) cells are mechanosensitive and have the potential to
differentiate into osteoblast‐like cells under the influence of cyclic tensile force (CTF). CTF …

Tooth development is regulated by sequential and reciprocal epithelium-mesenchymal
interactions and their related molecular signaling pathways, such as bone morphogenetic …

Eruption requires synchrony of the tooth with the surrounding tissues, particularly the bone.
One important step during eruption is remodelling of the alveolar bone at the base of the …

Background Periodontitis could lead to periodontal destruction such as the loss of alveolar
bone. The issue that how to achieve the regeneration of alveolar bone and periodontal …

The alveolar bone provides structural support against compressive and tensile forces
generated during mastication as well as during orthodontic treatment. To avoid abnormal …

Orthodontic tooth movement (OTM) is thought to be impeded by bisphosphonate (BP)
therapy, mainly due to increased osteoclast apoptosis and changes in the periodontal …

Periodontal ligament fibroblasts (PdLFs) exert important functions in oral tissue and bone
remodeling following mechanical forces, which are specifically applied during orthodontic …