Decreased food pleasure and disrupted satiety signals in chronic low back pain

P Geha, I DeAraujo, B Green, DM Small - PAIN®, 2014 - Elsevier
Chronic low back pain (CLBP) and obesity are interrelated, but the physiological
mechanisms linking the 2 conditions remain to be determined. Functional brain imaging …

[HTML][HTML] Chronic pain precedes disrupted eating behavior in low-back pain patients

Y Lin, I De Araujo, G Stanley, D Small, P Geha - PLoS One, 2022 - journals.plos.org
Chronic pain is associated with anhedonia and decreased motivation. These behavioral
alterations have been linked to alterations in the limbic brain and could explain the …

Reduced neural satiety responses in women affected by obesity

S Gobbi, SC Weber, G Graf, D Hinz, L Asarian, N Geary… - Neuroscience, 2020 - Elsevier
Overweight and obesity are major risk factors for a number of chronic diseases, including
diabetes, cardiovascular diseases, and cancer. Obesity rates are on the rise worldwide with …

Increased taste intensity perception exhibited by patients with chronic back pain

DM Small, AV Apkarian - Pain, 2006 - Elsevier
There is overlap between brain regions involved in taste and pain perception, and cortical
injuries may lead to increases as well as decreases in sensitivity to taste. Recently it was …

'Dis-comfort eating': an investigation into the use of food as a coping strategy for the management of chronic pain

I O'Loughlin, TRO Newton-John - Appetite, 2019 - Elsevier
Objectives Chronic pain and obesity are major public health concerns. Animal and human
models have demonstrated that eating high-sugar nutrient-dense foods confers analgesic …

Eating for pleasure or just wanting to eat? Reconsidering sensory hedonic responses as a driver of obesity

DJ Mela - Appetite, 2006 - Elsevier
Pleasure from foods can stimulate “non-homoeostatic” eating, and might therefore also
potentially contribute toward obesity. However, obesity is not reliably associated with …

[HTML][HTML] Neural correlates to food-related behavior in normal-weight and overweight/obese participants

A Ho, J Kennedy, A Dimitropoulos - 2012 - journals.plos.org
Two thirds of US adults are either obese or overweight and this rate is rising. Although the
etiology of obesity is not yet fully understood, neuroimaging studies have demonstrated that …

No evidence for an association between obesity and milkshake liking

KM Wall, MC Farruggia, EE Perszyk… - International journal of …, 2020 - nature.com
Background Prevailing models of obesity posit that hedonic signals override homeostatic
mechanisms to promote overeating in today's food environment. What researchers mean by …

Differences in brain responses between lean and obese women to a sweetened drink

L Connolly, K Coveleskie, LA Kilpatrick… - …, 2013 - Wiley Online Library
Background Ingestion of sweet food is driven by central reward circuits and restrained by
endocrine and neurocrine satiety signals. The specific influence of sucrose intake on central …

Dissatisfaction with own body makes patients with eating disorders more sensitive to pain

A Yamamotova, J Bulant, V Bocek… - Journal of pain …, 2017 - Taylor & Francis
Body image represents a multidimensional concept including body image evaluation and
perception of body appearance. Disturbances of body image perception are considered to …