The prefrontal cortex (PFC) provides executive top-down control of a variety of cognitive
processes. A distinctive feature of the PFC is its protracted structural and functional …

The prefrontal cortex (PFC) is a cortical brain region that regulates various cognitive
functions. One distinctive feature of the PFC is its protracted adolescent maturation, which is …

Neuroimmune mechanisms play critical roles in brain development and can be impacted by
early life adversity. Microglia are the resident immune cells in the brain, with both sex …

Microglia are the primary immune cells of the brain and function in multiple ways to facilitate
proper brain development. However, our current understanding of how these cells influence …

Adolescence is a highly vulnerable period for the emergence of major neuropsychological
disorders and is characterized by decreased cognitive control and increased risk-taking …

Dysfunction of both microglia and circuitry in the medial prefrontal cortex (mPFC) have been
implicated in numerous neuropsychiatric disorders, but how microglia affect mPFC …

In humans, excessive gestational weight gain during pregnancy is associated with an
increased risk for executive function deficits in the offspring. Our previous work has …

Most cognitive functions involving the prefrontal cortex emerge during late development.
Increasing evidence links this delayed maturation to the protracted timeline of prefrontal …

Disturbed neuronal activity in neuropsychiatric pathologies emerges during development
and might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic …

Microglia, the innate immune cells of the central nervous system, regulate brain
development by promoting cell genesis, pruning synapses, and removing dying, newly-born …