Regulation of whole bacterial pathogen transcription within infected hosts

MV La, D Raoult, P Renesto - FEMS microbiology reviews, 2008 - academic.oup.com
DNA microarrays are a powerful and promising approach to gain a detailed understanding
of the bacterial response and the molecular cross-talk that can occur as a consequence of …

Benefits and pitfalls of using microarrays to monitor bacterial gene expression during infection

JCD Hinton, I Hautefort, S Eriksson, A Thompson… - Current opinion in …, 2004 - Elsevier
The understanding of bacterial pathogenesis is dependent on techniques that elucidate the
underlying genetic and biochemical mechanisms. To study the mechanism of bacterial …

[HTML][HTML] Genomic-scale analysis of bacterial gene and protein expression in the host

JD Boyce, PA Cullen, B Adler - Emerging Infectious Diseases, 2004 - ncbi.nlm.nih.gov
The developing complementary technologies of DNA microarrays and proteomics are
allowing the response of bacterial pathogens to different environments to be probed at the …

Host gene expression profiling in pathogen–host interactions

H Hossain, S Tchatalbachev, T Chakraborty - Current opinion in …, 2006 - Elsevier
Microarray technology is a powerful high-throughput tool for the analysis of host–pathogen
interactions that permits simultaneous interrogation of the transcriptional status of thousands …

RNA profiling in host–pathogen interactions

SJ Waddell, PD Butcher, NG Stoker - Current opinion in microbiology, 2007 - Elsevier
The development of novel anti-bacterial treatment strategies will be aided by an increased
understanding of the interactions that take place between bacteria and host cells during …

Analysis of host responses to microbial infection using gene expression profiling

MF Kagnoff, L Eckmann - Current Opinion in Microbiology, 2001 - Elsevier
Gene expression profiling offers new opportunities for understanding host-cell responses to
microbial pathogens and their products. Current strategies involve either first identifying …

Functional and comparative genomics of pathogenic bacteria

GK Schoolnik - Current opinion in microbiology, 2002 - Elsevier
Microarray expression profiling and the development of data-mining tools and new statistical
instruments affords an unprecedented opportunity for the genome-scale study of bacterial …

Microarray analysis of bacterial pathogenicity

GK Schoolnik - 2002 - Elsevier
The DNA microarray, a surface that contains an ordered arrangement of each identified
open reading frame of a sequenced genome, is the engine of functional genomics. Its …

[HTML][HTML] Microarrays for studying the host transcriptional response to microbial infection and for the identification of host drug targets

D Yowe, WJ Cook, JC Gutierrez-Ramos - Microbes and infection, 2001 - Elsevier
It is essential to understand the molecular basis of a host's response to microbial infection so
that disease and tissue damage can be prevented. Modulation of host RNA expression is a …

How the host 'sees' pathogens: global gene expression responses to infection

ID Manger, DA Relman - Current Opinion in Immunology, 2000 - Elsevier
Innate immune responses to pathogens are believed to be patterned and stereotyped.
Adaptive responses display variety but in relatively few types of products and with limited …