Regulation of whole bacterial pathogen transcription within infected hosts
DNA microarrays are a powerful and promising approach to gain a detailed understanding
of the bacterial response and the molecular cross-talk that can occur as a consequence of …
of the bacterial response and the molecular cross-talk that can occur as a consequence of …
Benefits and pitfalls of using microarrays to monitor bacterial gene expression during infection
JCD Hinton, I Hautefort, S Eriksson, A Thompson… - Current opinion in …, 2004 - Elsevier
The understanding of bacterial pathogenesis is dependent on techniques that elucidate the
underlying genetic and biochemical mechanisms. To study the mechanism of bacterial …
underlying genetic and biochemical mechanisms. To study the mechanism of bacterial …
[HTML][HTML] Genomic-scale analysis of bacterial gene and protein expression in the host
The developing complementary technologies of DNA microarrays and proteomics are
allowing the response of bacterial pathogens to different environments to be probed at the …
allowing the response of bacterial pathogens to different environments to be probed at the …
Host gene expression profiling in pathogen–host interactions
H Hossain, S Tchatalbachev, T Chakraborty - Current opinion in …, 2006 - Elsevier
Microarray technology is a powerful high-throughput tool for the analysis of host–pathogen
interactions that permits simultaneous interrogation of the transcriptional status of thousands …
interactions that permits simultaneous interrogation of the transcriptional status of thousands …
RNA profiling in host–pathogen interactions
SJ Waddell, PD Butcher, NG Stoker - Current opinion in microbiology, 2007 - Elsevier
The development of novel anti-bacterial treatment strategies will be aided by an increased
understanding of the interactions that take place between bacteria and host cells during …
understanding of the interactions that take place between bacteria and host cells during …
Analysis of host responses to microbial infection using gene expression profiling
MF Kagnoff, L Eckmann - Current Opinion in Microbiology, 2001 - Elsevier
Gene expression profiling offers new opportunities for understanding host-cell responses to
microbial pathogens and their products. Current strategies involve either first identifying …
microbial pathogens and their products. Current strategies involve either first identifying …
Functional and comparative genomics of pathogenic bacteria
GK Schoolnik - Current opinion in microbiology, 2002 - Elsevier
Microarray expression profiling and the development of data-mining tools and new statistical
instruments affords an unprecedented opportunity for the genome-scale study of bacterial …
instruments affords an unprecedented opportunity for the genome-scale study of bacterial …
Microarray analysis of bacterial pathogenicity
GK Schoolnik - 2002 - Elsevier
The DNA microarray, a surface that contains an ordered arrangement of each identified
open reading frame of a sequenced genome, is the engine of functional genomics. Its …
open reading frame of a sequenced genome, is the engine of functional genomics. Its …
[HTML][HTML] Microarrays for studying the host transcriptional response to microbial infection and for the identification of host drug targets
D Yowe, WJ Cook, JC Gutierrez-Ramos - Microbes and infection, 2001 - Elsevier
It is essential to understand the molecular basis of a host's response to microbial infection so
that disease and tissue damage can be prevented. Modulation of host RNA expression is a …
that disease and tissue damage can be prevented. Modulation of host RNA expression is a …
How the host 'sees' pathogens: global gene expression responses to infection
ID Manger, DA Relman - Current Opinion in Immunology, 2000 - Elsevier
Innate immune responses to pathogens are believed to be patterned and stereotyped.
Adaptive responses display variety but in relatively few types of products and with limited …
Adaptive responses display variety but in relatively few types of products and with limited …