Abstract prodrugs are bioreversible derivatives of drug molecules that undergo
intermolecular or intramolecular reactions by enzymatic or chemical biotransformation in the …

Mutual prodrugs consisting of mefenamic acid with menthol and thymol have been
synthesized as a gastrosparing NSAIDs, devoid of ulcerogenic side effects. The structures of …

Objective: The purpose of the study was to synthesize prodrugs of mefenamic acid, to be
used as Anti inflammatory drug with fewer adverse effects. Methods: The drug was …

Background: Non steroidal anti-inflammatory drugs are the most widely prescribed drugs to
manage pain and inflammatory conditions, but their long term use is associated with …

This study deals with the synthesis, pharmacological activity, and kinetic studies of
mefenamic acid (MA) prodrugs of tyrosine and glycine. The synthesis involved a series of …

Prodrugs of mefenamic acid with natural compounds eugenol and vanillin have been
synthesized by dicyclohexylcarbodimide coupling method. Purified synthesized ester …

Background: The use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) is not up to its
potential because of their gastrointestinal side effects. Significant attention has been focused …

In order to reduce the gastrointestinal side effect, of mefenamic acid, its carboxylic group
was condensed with the hydroxyl group of 1, 2, 3-trihydroxy propane 1, 3 …

This review focuses on the design, synthesis and pharmacological effects of non-steroidal
anti-inflammatory (NSAIDs) mefenamic acid which is an anthranilic acid derivative …

Prodrugs or predrugs are inactive molecules which become active after in vivo conversion to
release the active parent drug. The prodrug's cleavage can be catalyzed by metabolic …