Glasslike membrane protein diffusion in a crowded membrane

I Munguira, I Casuso, H Takahashi, F Rico, A Miyagi… - ACS …, 2016 - ACS Publications
Many functions of the plasma membrane depend critically on its structure and dynamics.
Observation of anomalous diffusion in vivo and in vitro using fluorescence microscopy and …

Development of anomalous diffusion among crowding proteins

MR Horton, F Höfling, JO Rädler, T Franosch - Soft Matter, 2010 - pubs.rsc.org
In cell membranes, proteins and lipids diffuse in a highly crowded and heterogeneous
landscape, where aggregates and dense domains of proteins or lipids obstruct the path of …

Probing nanoscale diffusional heterogeneities in cellular membranes through multidimensional single-molecule and super-resolution microscopy

R Yan, K Chen, K Xu - Journal of the American Chemical Society, 2020 - ACS Publications
Diffusion properties notably determine the behavior of biomembranes. Here we report the
concurrent nanoscale fine-mapping of membrane topography, diffusivity, and packing order …

Anomalous and normal diffusion of proteins and lipids in crowded lipid membranes

M Javanainen, H Hammaren, L Monticelli… - Faraday …, 2013 - pubs.rsc.org
Lateral diffusion plays a crucial role in numerous processes that take place in cell
membranes, yet it is quite poorly understood in native membranes characterized by, eg …

Rotational diffusion of membrane proteins in crowded membranes

M Javanainen, OHS Ollila… - The Journal of Physical …, 2020 - ACS Publications
Membrane proteins travel along cellular membranes and reorient themselves to form
functional oligomers and protein–lipid complexes. Following the Saffman–Delbrück model …

Dynamics in the plasma membrane: how to combine fluidity and order

D Marguet, PF Lenne, H Rigneault, HT He - The EMBO journal, 2006 - embopress.org
Cell membranes are fascinating supramolecular aggregates that not only form a barrier
between compartments but also harbor many chemical reactions essential to the existence …

Correlating anomalous diffusion with lipid bilayer membrane structure using single molecule tracking and atomic force microscopy

MJ Skaug, R Faller, ML Longo - The Journal of chemical physics, 2011 - pubs.aip.org
Anomalous diffusion has been observed abundantly in the plasma membrane of biological
cells, but the underlying mechanisms are still unclear. In general, it has not been possible to …

Diffusion of integral membrane proteins in protein-rich membranes

M Javanainen, H Martinez-Seara… - The journal of …, 2017 - ACS Publications
The lateral diffusion of embedded proteins along lipid membranes in protein-poor conditions
has been successfully described in terms of the Saffman–Delbrück (SD) model, which …

[HTML][HTML] Effects of protein crowding on membrane systems

G Guigas, M Weiss - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2016 - Elsevier
Cellular membranes are typically decorated with a plethora of embedded and adsorbed
macromolecules, eg proteins, that participate in numerous vital processes. With typical …

Heterogeneous nanoscopic lipid diffusion in the live cell membrane and its dependency on cholesterol

YJ Chai, CY Cheng, YH Liao, CH Lin, CL Hsieh - Biophysical Journal, 2022 - cell.com
Cholesterol plays a unique role in the regulation of membrane organization and dynamics
by modulating the membrane phase transition at the nanoscale. Unfortunately, due to their …