[HTML][HTML] Polydeoxyribonucleotide, an Adenosine-A2A Receptor Agonist, Preserves Blood Testis Barrier from Cadmium-Induced Injury

F Squadrito, A Micali, M Rinaldi, N Irrera… - Frontiers in …, 2017 - frontiersin.org
Cadmium (Cd) impairs blood-testis barrier (BTB). Polydeoxyribonucleotide (PDRN), an
adenosine A2A agonist, has positive effects on male reproductive system. We investigated …

Retracted: Research Article Flavocoxid Protects Against Cadmium-Induced Disruption of the Blood-Testis Barrier and Improves Testicular Damage and Germ Cell …

L Minutoli, A Micali, A Pisani, D Puzzolo… - Toxicological …, 2015 - academic.oup.com
Cadmium (Cd) causes male infertility. There is the need to identify safe treatments
counteracting this toxicity. Flavocoxid is a flavonoid that induces a balanced inhibition of …

Effects of polydeoxyribonucleotide on the histological damage and the altered spermatogenesis induced by testicular ischaemia and reperfusion in rats

L Minutoli, P Antonuccio, F Squadrito… - … journal of andrology, 2012 - Wiley Online Library
The effects of polydeoxyribonucleotide (PDRN), an agonist of the A2A adenosine receptors
which when activated positively influences sperm activity, were tested in an experimental …

Cadmium inhibits mouse sperm motility through inducing tyrosine phosphorylation in a specific subset of proteins

L Wang, Y Li, J Fu, L Zhen, N Zhao, Q Yang, S Li… - Reproductive …, 2016 - Elsevier
Cadmium (Cd) has been reported to impair male fertility, primarily by disrupting sperm
motility, but the underlying molecular mechanism remains unclear. Here we investigated the …

Involvement of testicular DAAM1 expression in zinc protection against cadmium‐induced male rat reproductive toxicity

M Chemek, M Venditti, S Boughamoura… - Journal of cellular …, 2018 - Wiley Online Library
In order to verify the effects of exposure to Cd and Zn on testicular DAAM1 gene and protein
expression and also to ascertain their involvement in the protective role of Zn in prevent the …

Effect of cadmium on rat Leydig cell testosterone production and DNA integrity in vitro

LIU Qing, GUJ Hong, Y Yan, LIUX Zhong… - Biomedical and …, 2013 - besjournal.com
Cadmium (Cd) is an elemental heavy metal with widely recognized toxicity. Its long-term use
in industrial processes and daily activities has caused alarming levels of Cd contamination …

The traditional Chinese medicine Qiangjing tablet prevents blood‐testis barrier injury induced by CdCl2 through the PI3K/Akt/Rictor signaling pathway

Y Shen, Y You, K Zhu, G Li, X Huang… - Environmental …, 2023 - Wiley Online Library
Objective Environmental contaminants such as cadmium (Cd) may have a deleterious
impact on sperm and reduce male fertility by compromising the blood‐testis barrier (BTB) …

[HTML][HTML] Neuroendocrine effects of cadmium exposure on male reproductive functions

M Arteaga-Silva, E Arenas-Rios… - Frontiers in Bioscience …, 2020 - imrpress.com
In industrialized countries, the use of Cadmium (Cd) produces a form of anthropogenic
pollution. Hence, exposure by human populations is becoming a public health problem. With …

[HTML][HTML] Royal jelly abrogates cadmium-induced oxidative challenge in mouse testes: involvement of the Nrf2 pathway

RS Almeer, D Soliman, RB Kassab… - International Journal of …, 2018 - mdpi.com
The current study examined the efficacy of royal jelly (RJ) against cadmium chloride (CdCl2)-
induced testicular dysfunction. A total of 28 Swiss male mice were allocated into four groups …

[HTML][HTML] Protective effect of grape seed extract against cadmium-induced testicular dysfunction

A Alkhedaide, ZS Alshehri, A Sabry… - Molecular …, 2016 - spandidos-publications.com
Cadmium (Cd) is the most prevalent toxic metal present in livestock feed; therefore, the
present study aimed to examine the ameliorative effects of grape seed extract (GSE) on …