Relationship between seminal white blood cell counts and oxidative stress in men treated at an infertility clinic

RK SHARMA, FF PASQUALOTTO… - Journal of …, 2001 - Wiley Online Library
In semen, granulocytes are major producers of reactive oxygen species (ROS), which can
damage sperm. The diagnosis of leukocytospermia is usually based on the World Health …

A comparison between two assays for measuring seminal oxidative stress and their relationship with sperm DNA fragmentation and semen parameters

ST Homa, AM Vassiliou, J Stone, AP Killeen… - Genes, 2019 - mdpi.com
Oxidative stress (OS) is a significant cause of DNA fragmentation and is associated with
poor embryo development and recurrent miscarriage. The aim of this study was to compare …

Oxidative stress in normospermic men undergoing infertility evaluation

FF Pasqualotto, RK Sharma, H Kobayashi… - Journal of …, 2001 - Wiley Online Library
The purpose of this study was to determine whether normospermic infertile men have high
seminal oxidative stress, using 3 measures of oxidative stress: reactive oxygen species …

Positive myeloperoxidase staining (Endtz test) as an indicator of excessive reactive oxygen species formation in semen

M Shekarriz, RK Sharma, AJ Thomas… - Journal of assisted …, 1995 - Springer
Purpose Although the significance of leukocytospermia in semen remains controversial,
evidence exists that white blood cells (WBCs) may adversely affect sperm function and act …

Reactive oxygen species and sperm DNA damage in infertile men presenting with low level leukocytospermia

A Agarwal, A Mulgund, S Alshahrani, M Assidi… - Reproductive biology …, 2014 - Springer
Background Leukocytes contribute directly and indirectly to reactive oxygen species (ROS)
production. Although leukocytospermia is defined as the presence of≥ 1× 10 6 white blood …

Development of normal reference values for seminal reactive oxygen species and their correlation with leukocytes and semen parameters in a fertile population

KS Athayde, M Cocuzza, A Agarwal… - Journal of …, 2007 - Wiley Online Library
Although reactive oxygen species (ROSs) are clearly implicated in the pathogenesis of male
infertility, few studies have attempted to define the basal levels of ROSs in fertile men. Levels …

[HTML][HTML] Relationship between oxidative stress, semen characteristics, and clinical diagnosis in men undergoing infertility investigation

FF Pasqualotto, RK Sharma, DR Nelson… - Fertility and sterility, 2000 - Elsevier
Objective: To determine whether particular semen characteristics in various clinical
diagnoses of infertility are associated with high oxidative stress and whether any group of …

[HTML][HTML] Leukocytes and oxidative stress: dilemma for sperm function and male fertility

RR Henkel - Asian journal of andrology, 2011 - ncbi.nlm.nih.gov
Spermatozoa are constantly exposed to the interphase between oxidation through high
amounts of reactive oxygen species (ROS) and leukocytes, and reduction by means of …

Reference values of reactive oxygen species in seminal ejaculates using chemiluminescence assay

A Agarwal, G Ahmad, R Sharma - Journal of assisted reproduction and …, 2015 - Springer
Purpose A physiological balance exists between seminal reactive oxygen species (ROS)
and antioxidant capacity. An overproduction of ROS which exceeds the seminal plasma …

[HTML][HTML] Leukocytospermia is associated with increased reactive oxygen species production by human spermatozoa

RA Saleh, A Agarwal, E Kandirali, RK Sharma… - Fertility and sterility, 2002 - Elsevier
OBJECTIVE: To investigate the role of increased seminal leukocytes in enhancing reactive
oxygen species (ROS) production by human spermatozoa. DESIGN: A prospective study …