[HTML][HTML] Therapeutic drug monitoring in inflammatory bowel disease: The dawn of reactive monitoring

F Albader, PA Golovics, L Gonczi… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic condition that significantly affects the quality
of life of its patients. Biologic drugs have been the mainstay treatment in the management of …

[HTML][HTML] Updates in therapeutic drug monitoring in inflammatory bowel disease

N Lodhia, S Rao - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
Biologics and immunomodulators (IMM) are generally considered the most effective
therapies for the treatment of ulcerative colitis and Crohn's disease. However, despite the …

Multi-utility of therapeutic drug monitoring in inflammatory bowel diseases

CA Martins, KS Garcia, NSF Queiroz - Frontiers in Medicine, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) treatment targets have progressed over time from clinical
response to clinical and endoscopic remission. Several data have shown a positive …

A Review of Therapeutic Drug Monitoring in Patients with Inflammatory Bowel Disease Receiving Combination Therapy

S Patel, AJ Yarur - Journal of Clinical Medicine, 2023 - mdpi.com
Background: Inflammatory Bowel Disease (IBD) impacts millions worldwide, presenting a
major challenge to healthcare providers and patients. The advent of biologic therapies has …

Challenges in therapeutic drug monitoring: optimizing biological treatments in patients with inflammatory bowel disease and other immune-mediated inflammatory …

K Papamichael, G Stocco… - Therapeutic Drug …, 2023 - journals.lww.com
Background: Therapeutic drug monitoring (TDM) is a decision-making tool for optimizing the
use of certain therapies. In this article, the authors review the role of proactive TDM of …

Therapeutic drug monitoring in inflammatory bowel disease: for every patient and every drug?

K Papamichael, AS Cheifetz - Current opinion in gastroenterology, 2019 - journals.lww.com
For all biologics in IBD, there is a positive correlation between drug concentrations and
favorable therapeutic outcomes. Reactive TDM is the new standard of care for optimizing …

[HTML][HTML] Therapeutic drug monitoring of biologics for patients with inflammatory bowel diseases: How, When, and for Whom?

JF Wu - Gut and Liver, 2022 - ncbi.nlm.nih.gov
During the past decade, we have entered an era of biologics for the treatment of Crohn's
disease and ulcerative colitis. The therapeutic goal of inflammatory bowel disease (IBD) …

How, when, and for whom should we perform therapeutic drug monitoring?

S Vermeire, E Dreesen, K Papamichael… - Clinical …, 2020 - Elsevier
The implementation of therapeutic drug monitoring (TDM) in the inflammatory bowel disease
practice has evolved over the years. In the early days, the focus was merely on measuring …

Proactive therapeutic drug monitoring versus conventional management for inflammatory bowel diseases: a systematic review and meta-analysis

NH Nguyen, V Solitano, SK Vuyyuru, JK MacDonald… - Gastroenterology, 2022 - Elsevier
Background & Aims Proactive therapeutic drug monitoring (TDM) has been proposed to
improve outcomes in patients with inflammatory bowel disease (IBD) treated with tumor …

A practical guide to therapeutic drug monitoring of biologic medications for inflammatory bowel disease

BP Vaughn - Journal of Clinical Medicine, 2021 - mdpi.com
Therapeutic drug monitoring (TDM) is a useful strategy to optimize biologic medications for
inflammatory bowel disease not responsive to standard dosing regimens. TDM is cost …