Markers of increased oxidative stress are known to be elevated following acute myocardial
infarction and in the context of chronic left ventricular hypertrophy or heart failure, and their …

Chronic heart failure, secondary to left ventricular hypertrophy or myocardial infarction, is a
condition with increasing morbidity and mortality. Although the mechanisms underlying the …

Cardiac remodelling occurs in response to stress, such as chronic hypertension or
myocardial infarction, and forms the substrate for subsequent development of heart failure …

A heart under chronic stress undergoes cardiac remodelling, a process that comprises
structural and functional changes including cardiomyocyte hypertrophy, interstitial fibrosis …

Redox signaling refers to the specific and usually reversible oxidation/reduction modification
of molecules involved in cellular signaling pathways. In the heart, redox signaling regulates …

Heart failure and many of the conditions that predispose to heart failure are associated with
oxidative stress. This is considered to be important in the pathophysiology of the condition …

Heart failure (HF) occurs when the adaptation mechanisms of the heart fail to compensate
for stress factors, such as pressure overload, myocardial infarction, inflammation, diabetes …

Increased reactive oxygen species (ROS) production is implicated in the pathophysiology of
left ventricular (LV) hypertrophy and heart failure. However, the enzymatic sources of …

Increased activation of the renin–angiotensin–aldosterone system (RAAS) and an increase
in oxidative stress are both implicated in age-related cardiac remodeling but their precise …

Increases in oxidative stress in the heart play an important role in mediating hypertrophy,
apoptosis, fibrosis, mitochondrial dysfunction, and the consequent development of heart …