Until recently, two major forms of colorectal epithelial polyp were recognized: the adenoma
and the hyperplastic polyp. Adenomas were perceived to represent the precursor to …

The “serrated neoplastic pathway” describes the progression of serrated polyps, including
sessile serrated adenomas and traditional serrated adenomas, to colorectal cancer. The …

Until recently, two major types of colorectal epithelial polyps were distinguished: the
adenoma and the hyperplastic polyp. While adenomas—because of their cytological atypia …

Advances in our understanding of the molecular basis of colorectal cancer (CRC) have shed
new light on the nature of hyperplastic polyps and invite a reassessment of the relevance of …

Identification of the serrated neoplasia pathway has improved our understanding of the
pathogenesis of colorectal cancer (CRC). Insights include an increased recognition of the …

Our understanding of serrated colorectal polyps has increased dramatically over the past
two decades and has led to a modern classification scheme for these lesions. Sessile …

OBJECTIVES: Serrated polyps of the colorectum are a histologically and genetically
heterogeneous group of lesions, which include classic hyperplasic polyps, sessile serrated …

Colorectal cancer (CRC) is the third most frequently diagnosed cancer in the world. For a
long time, only one pathway of colorectal carcinogenesis was known. In recent years, a new …

Aim: To establish and explain the pattern of molecular signatures across colorectal polyps.
Methods and results: Thirty‐two sessile serrated adenomas (SSA), 10 mixed polyps (MP), 15 …

There is now strong evidence for an alternative pathway of colorectal carcinogenesis
implicating hyperplastic polyps and serrated adenomas. This article briefly reviews the …